LoKara Side Effects

Generic name: desonide topical

Medically reviewed by Drugs.com. Last updated on Feb 14, 2025.

Note: This document provides detailed information about LoKara Side Effects associated with desonide topical. Some dosage forms listed on this page may not apply specifically to the brand name LoKara.

Applies to desonide topical: topical application cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment.

Precautions

It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for any unwanted effects.

If your or your child's symptoms do not improve within a few days or after 4 weeks, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.

This medicine may affect your blood sugar levels. Check with your doctor right away if you have increased thirst or increased urination. If you notice a change in the results of your urine or blood sugar tests, or if you have any questions, check with your doctor.

Check with your doctor right away if blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

Check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Make sure your doctor knows that you are using desonide foam. You may need to stop using this medicine several days before having surgery.

Do not use cosmetics or other skin care products on the treated areas.

Common side effects of LoKara

Some side effects of desonide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of LoKara

Along with its needed effects, desonide topical (the active ingredient contained in LoKara) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking desonide topical:

For healthcare professionals

Applies to desonide topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment.

General adverse events

The most commonly reported side effects were headache, insomnia, impetigo, skin infection, and rash.^[Ref]

Endocrine

• Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome^[Ref]

Hypersensitivity

• Postmarketing reports: Allergic reaction including facial edema^[Ref]

Dermatologic

• Common (1% to 10%): Impetigo, skin infection, rash
• Frequency not reported: Folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria
• Postmarketing reports: Pruritus, skin disorder^[Ref]

Local

• Frequency not reported: Burning, itching, irritation, dryness^[Ref]

Other

• Common (1% to 10%): Flu syndrome aggravated^[Ref]

Nervous system

• Common (1% to 10%): Headache, insomnia^[Ref]

Metabolic

• Frequency not reported: Hyperglycemia, glucosuria, latent diabetes mellitus^[Ref]

See also:

Frequently asked questions

• What is Desonide cream used for?

Further information

LoKara side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer