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Levulan Kerastick Side Effects

Generic Name: aminolevulinic acid topical

Note: This document contains side effect information about aminolevulinic acid topical. Some of the dosage forms listed on this page may not apply to the brand name Levulan Kerastick.

For the Consumer

Applies to aminolevulinic acid topical: topical gel/jelly, topical kit, topical solution, topical stick

Along with its needed effects, aminolevulinic acid topical (the active ingredient contained in Levulan Kerastick) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aminolevulinic acid topical:

More common
  • Pain, burning, itching, redness, or swelling at the application site
Less common
  • Bleeding during lesion preparation
Incidence not known
  • Difficulty seeing at night
  • double vision
  • increased sensitivity of the eyes to sunlight
  • loss of memory
  • problems with memory
  • red, sore eyes
  • seeing double
  • swelling of the eyelids

Some side effects of aminolevulinic acid topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning, crawling, itching, numbness, prickling, “pins and needles,” stinging, or tingling feelings
  • darkening or lightening of the treated skin
  • scaling or crusting
  • skin sore
  • small, red, raised, itchy bumps
  • swelling of the skin
Less common
  • Blister
  • oozing
  • open sore on the skin
  • pain
  • pus filled blister or pimple
  • raw skin
  • scabbing
  • tenderness

For Healthcare Professionals

Applies to aminolevulinic acid topical: topical gel, topical solution


The most commonly reported side effects were scaling/crusting, hypo-/hyper-pigmentation, and itching.[Ref]


Very common (10% or more): Scaling/Crusting (up to 71%), hypo-/hyper-pigmentation (up to 36%), erosion (up to 14%), itching (up to 25%), pruritus
Common (1% to 10%): Wheal/flare, skin disorders NOS, ulceration, bleeding/hemorrhage, vesiculation, pustules, dysesthesia, scabbing, excoriation, oozing, skin tightness
Uncommon (0.1% to 1%): Pustular rash, dry skin, petechiae, hyperkeratosis[Ref]


Very Common (10% or more): Irritation, erythema, pain, edema, exfoliation, induration
Common (1% to 10%): Pain, tenderness, ulceration
Uncommon (0.1% to 1%): Discharge, discoloration, ulcer, chills, feeling hot, pyrexia, wound secretion

Nervous system

Common (1% to 10%): Headache, paraesthesia, hyperalgesia[Ref]


Uncommon (0.1% to 1%): Eyelid edema[Ref]


Uncommon (0.1% to 1%): Nervousness[Ref]


1. "Product Information. Levulan Kerastick (aminolevulinic acid)" Berlex, Richmond, CA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of Levulan Kerastick may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.