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Levulan Kerastick Side Effects

Generic name: aminolevulinic acid topical

Medically reviewed by Last updated on Jan 9, 2024.

Note: This document contains side effect information about aminolevulinic acid topical. Some dosage forms listed on this page may not apply to the brand name Levulan Kerastick.

Applies to aminolevulinic acid topical: topical gel/jelly, topical solution.

Serious side effects of Levulan Kerastick

Along with its needed effects, aminolevulinic acid topical (the active ingredient contained in Levulan Kerastick) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aminolevulinic acid topical:

More common

Less common

Incidence not known

Other side effects of Levulan Kerastick

Some side effects of aminolevulinic acid topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to aminolevulinic acid topical: topical gel, topical solution.


The most commonly reported side effects were scaling/crusting, hypo-/hyper-pigmentation, and itching.[Ref]


Very common (10% or more): Scaling/Crusting (up to 71%), hypo-/hyper-pigmentation (up to 36%), erosion (up to 14%), itching (up to 25%), pruritus

Common (1% to 10%): Wheal/flare, skin disorders NOS, ulceration, bleeding/hemorrhage, vesiculation, pustules, dysesthesia, scabbing, excoriation, oozing, skin tightness

Uncommon (0.1% to 1%): Pustular rash, dry skin, petechiae, hyperkeratosis[Ref]


Very Common (10% or more): Irritation, erythema, pain, edema, exfoliation, induration

Common (1% to 10%): Pain, tenderness, ulceration

Uncommon (0.1% to 1%): Discharge, discoloration, ulcer, chills, feeling hot, pyrexia, wound secretion

Nervous system

Common (1% to 10%): Headache, paraesthesia, hyperalgesia[Ref]


Uncommon (0.1% to 1%): Eyelid edema[Ref]


Uncommon (0.1% to 1%): Nervousness[Ref]


1. (2001) "Product Information. Levulan Kerastick (aminolevulinic acid)." Berlex Laboratories

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.