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Infed Side Effects

Generic Name: iron dextran

Note: This page contains information about the side effects of iron dextran. Some of the dosage forms included on this document may not apply to the brand name Infed.

For the Consumer

Applies to iron dextran: injectable solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking iron dextran (the active ingredient contained in Infed) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Iron dextran can cause severe and sometimes fatal allergic reactions or severely low blood pressure. Tell your caregiver right away if you feel light-headed or if you suddenly have trouble breathing.

Call your doctor at once if you have:

  • fast or slow heartbeats. chest pain, wheezing, trouble breathing;

  • a light-headed feeling, like you might pass out;

  • flushing (warmth, redness, or tingly feeling);

  • blue-colored lips or fingernails;

  • red or pink urine;

  • weak or shallow breathing (breathing may stop);

  • seizure (convulsions);

  • swelling, warmth, redness, or itching where the medicine was injected; or

  • delayed effect (1-2 days after injection)--fever, chills, dizziness, headache, general ill feeling, nausea and vomiting, joint or muscle pain, back pain.

Common side effects may include:

  • mild itching or rash;

  • body aches, numbness or tingly feeling;

  • nausea, vomiting, stomach pain, diarrhea;

  • mild dizziness or weakness, low fever; or

  • brown discoloration of your skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to iron dextran: injectable solution

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylactoid reactions (including dyspnea, urticaria, rashes, itching, nausea, and shivering)
Very rare (less than 0.01%): Acute severe anaphylactoid reactions (sudden onset of respiratory difficulty and/or cardiovascular collapse)
Frequency not reported: Anaphylactic reactions, fatal anaphylactic reactions[Ref]

Dermatologic

Uncommon (0.1% to 1%): Flushing, pruritus, rash
Rare (less than 0.1%): Angioedema, sweating
Frequency not reported: Urticaria, purpura[Ref]

Nervous system

Uncommon (0.1% to 1%): Numbness
Rare (less than 0.1%): Loss of consciousness, seizure, dizziness, tremor
Very rare (less than 0.01%): Headache, paresthesia
Frequency not reported: Convulsions, syncope, unresponsiveness, altered taste[Ref]

Musculoskeletal

Uncommon (0.1% to 1%): Cramps
Rare (less than 0.1%): Myalgias
Frequency not reported: Arthralgia, exacerbation of joint pain, arthritis, backache[Ref]

Other

Uncommon (0.1% to 1%): Feeling hot
Rare (0.01% to 0.1%): Fatigue, chest pain
Very rare (less than 0.01%): Transient deafness
Frequency not reported: Fever, weakness, febrile episodes, chills[Ref]

Respiratory

Uncommon (0.1% to 1%): Dyspnea
Frequency not reported: Respiratory arrest, bronchospasm, wheezing[Ref]

Ocular

Uncommon (0.1% to 1%): Blurred vision[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, emesis, abdominal pain
Rare (less than 0.1%): Diarrhea
Frequency not reported: Vomiting[Ref]

Cardiovascular

Rare (0.01 to 0.1%): Arrhythmia, tachycardia, hypotension
Very rare (less than 0.01%): Bradycardia, palpitations, hypertension
Frequency not reported: Chest tightness, shock, cyanosis, cardiac arrest[Ref]

Local

Rare (less than 0.1%): Pain and brown pigmentation at injection site
Frequency not reported: Soreness or inflammation at or near injection site, local phlebitic reaction, staining of the skin, bleeding, formation of sterile abscesses, tissue necrosis, atrophy, pain, sterile abscess, cellulitis[Ref]

Hematologic

Very rare (less than 0.01%): Hemolysis
Frequency not reported: Leukocytosis, lymphadenopathy[Ref]

Psychiatric

Rare (less than 0.1%): Restlessness, mental status changes
Frequency not reported: Disorientation[Ref]

Oncologic

Frequency not reported: Tumors at the injection site[Ref]

Genitourinary

Frequency not reported: Hematuria[Ref]

References

1. "Product Information. DexFerrum (iron dextran)." American Regent Laboratories Inc, Shirley, NY.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. INFeD (iron dextran)." Schein Pharmaceuticals Inc, Florham Park, NJ.

Not all side effects for Infed may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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