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Iron dextran Pregnancy and Breastfeeding Warnings

Iron dextran is also known as: Dexferrum, Infed

Medically reviewed on May 1, 2018

Iron dextran Pregnancy Warnings

Animal studies have shown teratogenic and embryocidal outcomes at about 3 times the maximum human dose. No consistent adverse fetal effects were seen at doses of 50 mg/kg or less in animal models. Animal models were not iron deficient. There are no controlled data in human pregnancy. It appears that some iron does cross the placenta, but the form of the iron that crosses is not clear.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is recommended only if clearly needed and the benefit outweighs the risk.
Use is not recommended during the first trimester of pregnancy.

US FDA pregnancy category: C

Comments:
-Iron deficiency anemia during the first trimester can frequently be treated with oral iron.

See references

Iron dextran Breastfeeding Warnings

Use is not recommended.

Excreted into human milk: Yes

Comments:
-Traces of unmetabolized drug are excreted in human milk.

See references

References for pregnancy information

  1. "Product Information. DexFerrum (iron dextran)." American Regent Laboratories Inc, Shirley, NY.
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. INFeD (iron dextran)." Schein Pharmaceuticals Inc, Florham Park, NJ.

References for breastfeeding information

  1. "Product Information. INFeD (iron dextran)." Schein Pharmaceuticals Inc, Florham Park, NJ.
  2. "Product Information. DexFerrum (iron dextran)." American Regent Laboratories Inc, Shirley, NY.
  3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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