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Iron Dextran use while Breastfeeding

Drugs containing Iron Dextran: Infed, Dexferrum

Medically reviewed by Drugs.com. Last updated on Feb 24, 2021.

Iron Dextran Levels and Effects while Breastfeeding

Summary of Use during Lactation

Limited data indicate that trace amounts of iron dextran are excreted into breastmilk. No information is available on the clinical use of iron dextran during breastfeeding. However, intravenous iron dextran has been used in preterm infants for anemia of prematurity and would not be expected to cause any adverse effects in breastfed infants. An alternate intravenous drug with more published data available may be preferred. Pasteurization of milk by the Holder method reduces the concentration of iron in milk by about 6.5%.[1]

Drug Levels

Maternal Levels.Relevant published information was not found as of the revision date. Iron dextran manufacturers report that trace amounts of unmetabolized iron dextran are excreted into human milk.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Ferric Carboxymaltose, Iron Sucrose

References

1.
Mohd-Taufek N, Cartwright D, Davies M et al. The effect of pasteurization on trace elements in donor breast milk. J Perinatol. 2016;36:897-900. [PubMed: 27253894]

Substance Identification

Substance Name

Iron Dextran

CAS Registry Number

9004-66-4

Drug Class

  • Breast Feeding
  • Lactation
  • Ferric Compounds
  • Hematinics

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Further information

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