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Generic Name: ferric citrate (FER ik SIT rate)
Brand Name: Auryxia

What is Auryxia?

Auryxia contains iron that binds to the phosphates you take in through food, which helps your body absorb fewer phosphates. This can lower the amount of phosphorus (a mineral) in your blood.

Auryxia is used to control phosphorus levels in adults with chronic kidney disease who are on dialysis.

Auryxia is also used to treat iron deficiency anemia in adults with chronic kidney disease who are not on dialysis.

Auryxia may also be used for purposes not listed in this medication guide.

Important Information

Keep this medicine out of the reach of children. An accidental overdose of Auryxia by a child can be fatal.

Before taking this medicine

You should not use Auryxia if you are allergic to it, or if you have:

To make sure Auryxia is safe for you, tell your doctor if you have ever had:

  • liver disease;

  • a stomach or intestinal disorder;

  • stomach bleeding; or

  • stomach or intestinal surgery.

It is not known whether this medicine will harm an unborn baby. An overdose of iron can cause miscarriage, birth defects, or pregnancy-related diabetes. Tell your doctor if you are pregnant or plan to become pregnant while taking this medicine.

It is not known whether Auryxia passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Your dose needs may be different during pregnancy or while you are nursing.

This medicine is not approved for use by anyone younger than 18 years old.

How should I take Auryxia?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not crush or chew a Auryxia tablet. The pill may discolor your teeth or mouth.

Auryxia works best if you take it with meals.

Auryxia contains iron, which is absorbed and stored by your body while you are taking this medicine. To make sure your body is not storing too much iron, you will need frequent blood tests to check your iron levels.

Auryxia may be only part of a complete program of treatment that also includes a special diet. Follow the diet plan created for you by your doctor or nutrition counselor. Get familiar with the list of foods you should eat or avoid to help control your condition.

Store this medicine in the original container at room temperature away from moisture and heat.

Keep the bottle tightly closed and out of the reach of children. Accidental iron overdose is a leading cause of death in children younger than 6 years old.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of iron can be fatal to a child who accidentally consumes this medicine.

What should I avoid while taking Auryxia?

Avoid taking other medicines at the same time of day with Auryxia. If you also take an antibiotic called doxycycline, take it at least 1 hour before you take this medicine. If you take an antibiotic called ciprofloxacin, take it at least 2 hours before or 2 hours after you take this medicine.

Do not take a vitamin or mineral supplement that contains iron while you are taking Auryxia, unless your doctor has told you to.

Auryxia side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe stomach problems (pain, vomiting, diarrhea); or

  • high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

  • diarrhea, constipation;

  • darker color in your bowel movements;

  • nausea, vomiting, stomach pain; or

  • cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Auryxia?

Other drugs may interact with ferric citrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Auryxia.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.

Last reviewed: November 09, 2017
Date modified: March 06, 2018