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Histex-AC Side Effects

Generic Name: codeine / phenylephrine / triprolidine

Note: This document contains side effect information about codeine / phenylephrine / triprolidine. Some of the dosage forms listed on this page may not apply to the brand name Histex-AC.

For the Consumer

Applies to codeine/phenylephrine/triprolidine: oral liquid

Warning

Codeine can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

This medicine is not for use in anyone under 18.

You should not use antihistamine medication to make a child sleepy.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

Stop taking this medicine and call your doctor at once if you have:

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

  • dizziness, drowsiness, tired feeling;

  • dry mouth, nose, or throat;

  • blurred vision;

  • nausea, vomiting, constipation; or

  • sleep problems (insomnia).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to codeine/phenylephrine/triprolidine: oral liquid

General

The most commonly occurring side effects include dry mouth, dizziness, sleepiness, and disturbed coordination.[Ref]

Cardiovascular

Frequency not reported: Hypotension, palpitations, tachycardia, extrasystoles

Gastrointestinal

Frequency not reported: Dry mouth, dry throat, epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation

Genitourinary

Frequency not reported: Urinary frequency, difficult urination, urinary retention

Psychiatric

Frequency not reported: Confusion, restlessness, excitation, anxiety, nervousness, irritability, insomnia, euphoria, hysteria, hallucination

Ocular

Frequency not reported: Blurred vision, diplopia

Other

Frequency not reported: Chills, fatigue, vertigo, tinnitus

Dermatologic

Frequency not reported: Drug rash, photosensitivity, excessive perspiration, urticaria

Nervous system

Frequency not reported: Sedation, sleepiness, dizziness, disturbed coordination, tremor, paresthesias, neuritis, convulsions, CNS depression

Respiratory

Frequency not reported: Nasal dryness, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness, respiratory depression

References

1. "American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults." J Am Geriatr Soc 63 (2015): 2227-46

2. "Product Information. Histex-AC (codeine / phenylephrine / triprolidine)." Allegis Pharmaceuticals, Canton, MS.

More about Histex-AC (codeine / phenylephrine / triprolidine)

Consumer resources

Related treatment guides

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.