Galcanezumab Side Effects

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 6, 2024.

Applies to galcanezumab: subcutaneous solution.

Common side effects of galcanezumab

Some side effects of galcanezumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Serious side effects of galcanezumab

Along with its needed effects, galcanezumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking galcanezumab:

Incidence not known

• difficulty breathing
• fast heartbeat
• fever
• hives, itching, skin rash
• hoarseness
• irritation
• joint pain, stiffness, or swelling
• redness of the skin
• swelling of the eyelids, face, lips, hands, or feet
• tightness in the chest
• trouble with swallowing

For healthcare professionals

Applies to galcanezumab: subcutaneous solution.

General adverse events

The most commonly reported adverse reaction has been injection site reactions.^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions (including dyspnea, urticaria, and rash)
• Postmarketing reports: Anaphylaxis, angioedema^[Ref]

Immunologic

• Very common (10% or more): Anti-Drug-Antibodies (up to 12.5%)^[Ref]

Local

• Very common (10% or more): Injection site reactions (18%)^[Ref]

Injection site reaction included event terms such as injection site pain, injection site reaction, injection site erythema, and injection site pruritus.^[Ref]

Other

• Common (1% to 10%): Vertigo

Dermatologic

• Common (1% to 10%): Pruritus
• Uncommon (0.1% to 1%): Urticaria
• Postmarketing reports: Rash

Gastrointestinal

• Common (1% to 10%): Constipation

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Further information

Galcanezumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer