Skip to Content

Galantamine Side Effects

In Summary

Commonly reported side effects of galantamine include: nausea and vomiting. Other side effects include: dizziness, dyspepsia, fatigue, headache, weight loss, diarrhea, and anorexia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to galantamine: oral capsule extended release, oral solution, oral tablet

In addition to its needed effects, some unwanted effects may be caused by galantamine. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking galantamine:

Less common:
  • Chest pain or discomfort
  • lightheadedness, dizziness, or fainting
  • shakiness in the legs, arms, hands, or feet
  • shortness of breath
  • slow or irregular heartbeat
  • unusual tiredness
  • Blurred vision
  • confusion
  • decreased urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • fainting
  • fast, irregular, pounding, or racing heartbeat or pulse
  • feeling of warmth
  • rapid breathing
  • redness of the face, neck, arms, and occasionally, upper chest
  • sunken eyes
  • sweating
  • thirst
  • troubled breathing
  • unusual tiredness or weakness
  • wrinkled skin
Incidence not known:
  • Blistering, peeling, or loosening of the skin
  • chills
  • cough
  • dark urine
  • fever
  • general tiredness and weakness
  • headache
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • light-colored stools
  • nausea and vomiting
  • nervousness
  • pounding in the ears
  • rash, hives, or itching skin
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled swallowing
  • upper right abdominal or stomach pain
  • yellow eyes and skin

If any of the following symptoms of overdose occur while taking galantamine, get emergency help immediately:

Symptoms of overdose:
  • Confusion
  • convulsions
  • irregular, fast or slow, or shallow breathing
  • muscle weakness
  • pale or blue lips, fingernails, or skin
  • severe nausea
  • stomach cramps
  • sweating
  • tearing of the eyes
  • twitches of the muscle visible under the skin
  • vomiting

Minor Side Effects

Some of the side effects that can occur with galantamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Decreased appetite
  • weight loss
Less common:
  • Acid or sour stomach
  • belching
  • discouragement
  • feeling sad or empty
  • general feeling of discomfort or illness
  • heartburn
  • increased sweating
  • indigestion
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle spasms
  • stomach discomfort, upset, or pain
  • trouble concentrating
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • dry heaves
  • loss of taste
  • unusually deep sleep
  • unusually long duration of sleep
Incidence not known:
  • Continuing ringing or buzzing or other unexplained noise in the ears
  • hearing loss
  • seeing, hearing, or feeling things that are not there

For Healthcare Professionals

Applies to galantamine: oral capsule extended release, oral solution, oral tablet


Common (1% to 10%): Bradycardia
Uncommon (0.1% to 1%): First degree atrioventricular block, palpitations, sinus bradycardia, supraventricular extrasystoles, flushing, hypotension
Frequency not reported: Postural hypotension, dependent edema, cardiac failure, myocardial ischemia or infarction, atrial arrhythmias including atrial fibrillation and supraventricular tachycardia, QT prolonged, bundle branch block, T-wave inversion, chest pain and ventricular tachycardia
Postmarketing reports: Hypertension[Ref]


Common (1% to 10%): Hyperhidrosis


Very common (10% or more): Nausea, vomiting
Common (1% to 10%): Diarrhea, abdominal pain, upper abdominal pain, dyspepsia, stomach discomfort, abdominal discomfort
Uncommon (0.1% to 1%): Retching
Postmarketing reports: Upper and lower GI bleeding, stomach discomfort, and abdominal discomfort.[Ref]


The most common side effects associated with discontinuation were nausea, vomiting, decreased appetite, dizziness, diarrhea, headache, decreased weight, and abdominal pain.[Ref]


Common (1% to 10%): Urinary tract infection, hematuria
Frequency not reported: Increased libido[Ref]


Common (1% to 10%): Anemia[Ref]


Postmarketing reports: Hepatitis, increased hepatic enzymes


Postmarketing reports: Hypersensitivity


Common (1% to 10%): Decreased appetite, decreased weight, anorexia
Uncommon (0.1% to 1%): Dehydration


Common (1% to 10%): Muscle spasms
Uncommon (0.1% to 1%): Muscular weakness

Nervous system

Common (1% to 10%): Dizziness, headache, tremor, syncope, lethargy, somnolence
Uncommon (0.1% to 1%): Dysgeusia, hypersomnia, paresthesia
Frequency not reported: Insomnia, leg cramps, transient ischemic attacks, cerebrovascular accidents
Postmarketing reports: Tinnitus[Ref]


Uncommon (0.1% to 1%): Blurred vision


Common (1% to 10%): Fatigue, asthenia, malaise
Uncommon (0.1% to 1%): Fall
Frequency not reported: Death in patients with mild cognitive impairment, fever


Common (1% to 10%): Depression
Frequency not reported: Apathy, paranoia (disagreeable or terrifying dreams), paranoid reaction, increased libido, delirium, suicidal ideation and suicide
Postmarketing reports: Hallucination, visual hallucination, auditory hallucination[Ref]


Common (1% to 10%): Rhinitis[Ref]


1. "Product Information. Reminyl (galantamine)" Janssen Pharmaceuticals, Titusville, NJ.

2. "Product Information. Razadyne (galantamine)." Ortho McNeil Pharmaceutical, Raritan, NJ.

3. Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." J Am Geriatr Soc 57 (2009): 565

Not all side effects for galantamine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.