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Finerenone Side Effects

Medically reviewed by Last updated on Oct 11, 2023.

Applies to finerenone: oral tablet.

Serious side effects of Finerenone

Along with its needed effects, finerenone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking finerenone:

More common

Less common

For Healthcare Professionals

Applies to finerenone: oral tablet.


The most frequently reported adverse reaction was hyperkalemia.[Ref]


Common (1% to 10%): Hypotension (includes blood pressure decreased, diastolic blood pressure decreased, diastolic hypotension, hypotension)

Frequency not reported: Systolic blood pressured decreased, diastolic blood pressure decreased[Ref]

In patients treated with this drug, the mean systolic and diastolic blood pressure decreased by 2 to 4 mmHg and 1 to 2 mmHg, respectively, at month 1 and remained stable thereafter. Most hypotension events were mild or moderate and resolved; events associated with hypotension (e.g., dizziness, syncope, fall) were not more frequent in patients treated with this drug compared to placebo.[Ref]


Common (1% to 10%): Pruritus[Ref]


Common (1% to 10%): Anemia

Uncommon (0.1% to 1%): Hemoglobin decreased

Frequency not reported: Hematocrit decreased[Ref]


Very common (10% or more): Serum potassium increased (up to 21.7%), hyperkalemia (includes blood potassium increased, hyperkalemia; up to 18.3%)

Common (1% to 10%): Hyponatremia (includes blood sodium decreased, hyponatremia)[Ref]

In a study, hyperkalemia events were reported in 18.3% of patients treated with this drug; most hyperkalemia events were mild to moderate in patients treated with this drug. Serious hyperkalemia events were report more often for this drug than placebo; serum potassium levels greater than 5.5 mmol/L and greater than 6 mmol/L were reported in 21.7% and 4.5% of patients treated with this drug and in 9.8% and 1.4% of those treated with placebo, respectively.

An increase from baseline in mean serum potassium in the first month of therapy was about 0.2 mmol/L in patients treated with this drug.[Ref]

Nervous system

Frequency not reported: Dizziness, syncope[Ref]


Frequency not reported: Fall[Ref]


Common (1% to 10%): Estimated glomerular filtration rate (eGFR) decreased/GFR decreased[Ref]

This drug caused an initial small decrease in eGFR (mean 2 mL/min/1.73 m2); it occurred within the first 4 weeks of therapy and then stabilized. In a study including patients with chronic kidney disease associated with type 2 diabetes, this decrease was reversible after therapy was stopped.[Ref]


1. (2022) "Product Information. Kerendia (finerenone)." Bayer Plc

2. (2021) "Product Information. Kerendia (finerenone)." Bayer Pharmaceutical Inc

3. (2021) "Product Information. Kerendia (finerenone)." Bayer Australia Ltd, 1.0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.