Evekeo Side Effects
Generic name: amphetamine
Medically reviewed by Drugs.com. Last updated on Sep 10, 2023.
Note: This document provides detailed information about Evekeo Side Effects associated with amphetamine. Some dosage forms listed on this page may not apply specifically to the brand name Evekeo.
Applies to amphetamine: oral suspension extended release, oral tablet, oral tablet disintegrating, oral tablet extended release chewable, oral tablet extended release disintegrating.
Important warnings
This medicine can cause some serious health issues
Serious side effects of Evekeo
Along with its needed effects, amphetamine (the active ingredient contained in Evekeo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking amphetamine:
More common
- agitation
- anxiety
- bladder pain
- bloody or cloudy urine
- crying
- delusions of persecution, mistrust, suspiciousness, or combativeness
- difficult, burning, or painful urination
- false or unusual sense of well-being
- feeling of unreality
- frequent urge to urinate
- lower back or side pain
- mental depression
- nervousness
- quick to react or overreact emotionally
- rapidly changing moods
- sense of detachment from self or body
Less common
- chills
- cough
- fever
- hoarseness
Rare
- seeing, hearing, or feeling things that are not there
- severe mental changes
Incidence not known
- blistering, peeling, loosening of the skin
- blurred vision
- chest pain or discomfort
- confusion
- dark urine
- diarrhea
- difficulty breathing
- dizziness
- fainting
- fast, irregular, pounding, or racing heartbeat or pulse
- headache
- hives, itching, skin rash
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- mood swings
- muscle cramps, pain, stiffness, or spasms
- nausea
- overactive reflexes
- pain or discomfort in the arms, jaw, back, or neck
- paleness or cold feeling in the fingertips and toes
- pounding in the ears
- red skin lesions, often with a purple center
- red, irritated eyes
- restlessness
- shakiness in the legs, arms, hands, or feet
- shivering
- slow or fast heartbeat
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- sweating
- swelling of the feet or lower legs
- talking or acting with excitement you cannot control
- tingling or pain in the fingers or toes when exposed to cold temperatures
- trouble sleeping
- twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
- uncontrolled vocal outbursts or tics (uncontrolled repeated body movements)
- unusual tiredness or weakness
- vomiting
Get emergency help immediately if any of the following symptoms of overdose occur while taking amphetamine:
Symptoms of overdose
- aggressive
- agitation
- angry
- blurred vision
- change in consciousness
- chest pain or discomfort
- confusion
- dark urine
- diarrhea
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- extremely high fever or body temperature
- fainting
- fast breathing
- fast, slow, or irregular heartbeat
- headache
- inability to speak
- loss of bladder control
- loss of consciousness
- muscle cramps, spasms, jerking, pain, or stiffness
- nausea
- nervousness
- overactive reflexes
- pain or discomfort in the arms, jaw, back, or neck
- pale, clammy skin
- palpitations
- panic states
- physical attempt to injure
- poor coordination
- pounding in the ears
- restlessness
- seeing, hearing, or feeling things that are not there
- seizures
- shakiness in the legs, arms, hands, or feet
- shivering
- slurred speech
- stomach cramps
- sudden loss of consciousness
- sweating
- swelling of the feet or lower legs
- talking or acting with excitement you cannot control
- temporary blindness
- thirst
- trembling or shaking of the hands or feet
- unusual tiredness or weakness
- violent actions
- vomiting
- weakness in the arm or leg on one side of the body, sudden and severe
Other side effects of Evekeo
Some side effects of amphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- dry mouth
- loss of appetite
- stomach ache
- voice changes
- weight loss
Less common
- belching
- heartburn
- indigestion
- stomach discomfort, upset, or pain
Incidence not known
- constipation
- decreased interest in sexual intercourse
- difficulty having a bowel movement
- inability to have or keep an erection
- loss in sexual ability, desire, drive, or performance
- redness of the skin
- thinning or loss of hair
- unpleasant taste
For healthcare professionals
Applies to amphetamine: oral suspension extended release, oral tablet, oral tablet disintegrating, oral tablet disintegrating extended release, oral tablet extended release.
General
The most commonly reported side effects with amphetamine (the active ingredient contained in Evekeo) products include dry mouth, anorexia, weight loss, abdominal pain, nausea, insomnia, restlessness, emotional lability, dizziness, and tachycardia.[Ref]
Cardiovascular
- Frequency not reported: Palpitations, tachycardia, elevated blood pressure, cardiomyopathy
- Postmarketing reports: Peripheral vasculopathy, myocardial infarction, sudden death, Raynaud's phenomenon[Ref]
There have been isolated reports of cardiomyopathy associated with chronic amphetamine use.[Ref]
Hypersensitivity
- Postmarketing reports: Hypersensitivity reactions including angioedema and anaphylaxis
Dermatologic
- Postmarketing reports: Urticaria, rash, serious skin rashes, including Stevens-Johnson Syndrome and toxic epidermal necrolysis, alopecia
Psychiatric
- Rare (less than 0.1%): Psychotic episodes
- Frequency not reported: Euphoria, dysphoria, insomnia, restlessness, irritability, depression, aggression, anger, logorrhea, dermatillomania[Ref]
Nervous system
- Frequency not reported: Overstimulation, dizziness, dyskinesia, tremor, headache, exacerbation of motor/phonic tics and Tourette's syndrome, paresthesia, formication[Ref]
Musculoskeletal
- Postmarketing reports: Rhabdomyolysis[Ref]
Gastrointestinal
- Common (1% to 10%): Upper abdominal pain
- Frequency not reported: Dry mouth, unpleasant taste, diarrhea, constipation, other GI disturbances, bruxism[Ref]
Endocrine
Immunologic
- Frequency not reported: Urticaria[Ref]
Metabolic
- Frequency not reported: Anorexia, weight loss[Ref]
Respiratory
- Common (1% to 10%): Epistaxis, allergic rhinitis[Ref]
Ocular
- Postmarketing reports: Blurred vision, mydriasis[Ref]
References
1. (2019) "Product Information. Adzenys ER (amphetamine)." Neos Therepeautics, Inc
2. (2019) "Product Information. Adzenys XR-ODT (amphetamine)." Neos Therepeautics, Inc
3. (2021) "Product Information. Evekeo ODT (amphetamine)." Arbor Pharmaceuticals
4. (2015) "Product Information. Evekeo (amphetamine)." Arbor Pharmaceuticals
5. (2015) "Product Information. Dyanavel XR (amphetamine)." Tris Pharma Inc
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Patient resources
Other brands
Adzenys XR-ODT, Dyanavel XR, Adzenys ER, Evekeo ODT
Professional resources
Other brands
Adzenys XR-ODT, Dyanavel XR, Adzenys ER, Evekeo ODT
Related treatment guides
Further information
Evekeo side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.