Elahere Side Effects

Generic name: mirvetuximab soravtansine

Medically reviewed by Drugs.com. Last updated on Jul 4, 2024.

Note: This document provides detailed information about Elahere Side Effects associated with mirvetuximab soravtansine. Some dosage forms listed on this page may not apply specifically to the brand name Elahere.

Applies to mirvetuximab soravtansine: intravenous solution.

Serious side effects of Elahere

Along with its needed effects, mirvetuximab soravtansine (the active ingredient contained in Elahere) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking mirvetuximab soravtansine:

Other side effects of Elahere

Some side effects of mirvetuximab soravtansine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Receiving this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control to prevent pregnancy while you are receiving this medicine and for at least 7 months after the last dose. If you think you have become pregnant while receiving this medicine, tell your doctor right away.

This medicine may cause eye or vision problems (eg, visual impairment, keratopathy, dry eye, photophobia, eye pain, and uveitis). Check with your doctor right away if you have blurred vision, change in vision, difficulty seeing at night, eye pain, increased sensitivity of the eyes to sunlight, redness of the eye, or tearing. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

This medicine may cause pneumonitis (swelling of the lungs). Check with your doctor right away if you have chest pain, chills, cough, fever, general feeling of discomfort or illness, thickening of bronchial secretions, or trouble breathing

Check with your doctor right away if you are having burning, numbness, tingling, or painful sensations, weakness in the arms, hands, legs, or feet, or unsteadiness. These could be symptoms of a condition called peripheral neuropathy.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

For healthcare professionals

Applies to mirvetuximab soravtansine: intravenous solution.

General adverse events

The most common adverse reactions with a frequency of 20% or more, including laboratory abnormalities, were vision impairment, fatigue, increased aspartate aminotransferase, nausea, increased alanine aminotransferase, keratopathy, abdominal pain, decreased lymphocytes, peripheral neuropathy, diarrhea, decreased albumin, constipation, increased alkaline phosphatase, dry eye, decreased magnesium, decreased leukocytes, decreased neutrophils, and decreased hemoglobin.

The most common side effects resulting in discontinuation were intestinal obstruction (2%) and thrombocytopenia (2%).

Serious adverse reactions were reported in 31% of patients, of which the most common were intestinal obstruction, ascites, infection, and pleural effusion.^[Ref]

Gastrointestinal

• Very common (10% or more): Abdominal distension (11%), abdominal pain (36%), constipation (30%), diarrhea (31%), nausea (40%), vomiting (19%)^[Ref]

Hematologic

• Common (1% to 10%): Thrombocytopenia^[Ref]

Hypersensitivity

• Common (1% to 10%): Infusion related reactions/hypersensitivity^[Ref]

Musculoskeletal

• Very common (10% or more): Arthralgia (17%), myalgia (10%)^[Ref]

Nervous system

• Very common (10% or more): Peripheral neuropathy (33%)^[Ref]

Ocular

• Very common (10% or more): Cataract (18%), dry eye (27%), eye pain (10%), keratopathy (37%), photophobia (17%), vision impairment (50%)
• Common (1% to 10%): Uveitis^[Ref]

Other

• Very common (10% or more): Fatigue (49%)^[Ref]

Respiratory

• Very common (10% or more): Dyspnea (12%)
• Common (1% to 10%): Pneumonitis^[Ref]

Metabolic

• Very common (10% or more): Decreased appetite (18%)^[Ref]

See also:

Frequently asked questions

• What is the success rate of Elahere?

Further information

Elahere side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer