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Dihydrocodeine / phenylephrine Side Effects

Applies to dihydrocodeine/phenylephrine: oral liquid.


Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Get emergency medical help if you have any of these signs of an allergic reaction while taking dihydrocodeine / phenylephrine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dihydrocodeine / phenylephrine: oral liquid.

Nervous system

Nervous system side effects have included light-headedness, dizziness, drowsiness, headache, fatigue, sedation, confusion, hallucinations, vivid dreams, severe narcosis, lassitude, giddiness, increased irritability, and excitement.[Ref]


Gastrointestinal side effects have included nausea, vomiting, constipation, abdominal pain, dry mouth, indigestion, anorexia, and spasm of biliary tract.[Ref]


Dermatologic side effects have included sweating, pruritis, and skin reactions.[Ref]


Renal side effects have included granulomatous interstitial nephritis and acute renal failure.[Ref]


Cardiovascular side effects have included orthostatic hypotension and cardiac palpitations.[Ref]


Respiratory side effects have included cough suppression.[Ref]


Ocular side effects have included blurred vision.[Ref]


Hypersensitivity side effects have included anaphylactoid reactions.[Ref]


Genitourinary side effects have included urinary retention.[Ref]


1. (2008) "Product Information. Alahist DHC (dihydrocodeine-phenylephrine)." Poly Pharmaceuticals Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.