Dibent Side Effects
Generic Name: dicyclomine
Note: This page contains information about the side effects of dicyclomine. Some of the dosage forms included on this document may not apply to the brand name Dibent.
For the Consumer
Applies to dicyclomine: oral capsules and tablets, oral solution, parenteral injection
Side effects include:
Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.
Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; although adverse effects occasionally may be obviated by a reduction in dosage, this also will likely eliminate potential therapeutic effects. If dosage of ≥80 mg daily cannnot be achieved because of intolerance, discontinue dicyclomine (the active ingredient contained in Dibent)
Dry mouth, dizziness, blurred vision, nausea, light-headedness (especially with the injectable form), drowsiness, weakness, nervousness.
For Healthcare Professionals
Applies to dicyclomine: compounding powder, intramuscular solution, oral capsule, oral syrup, oral tablet
-The most serious adverse reactions include cardiovascular and central nervous system symptoms.
-The most common adverse reactions are dizziness, dry mouth, vision blurred, nausea, somnolence, asthenia and nervousness, fever, tachycardia, agitation, and dry skin/mucous membranes.[Ref]
Very common (10% or more): Dry mouth (33%), nausea (14%)
Rare (less than 0.1%): Constipation, anorexia
Frequency not reported: Thirst, delayed gastric emptying time, reduced gastric acid secretion, gastroesophageal reflux
Postmarketing reports: Abdominal distension, abdominal pain, dyspepsia, constipation, dry mouth, nausea, vomiting[Ref]
Very common (10% or more): Dizziness (40%)
Common (1% to 10%): Somnolence, nervousness
Rare (less than 0.1%): Sedation, headache
Postmarketing reports: Dizziness, headache, somnolence, syncope[Ref]
Very common (10% or more): Blurred vision (27%)
Frequency not reported: Follicular conjunctivitis, all muscarinic antagonists can precipitate glaucoma
Postmarketing reports: Cycloplegia, mydriasis, blurred vision[Ref]
Common (1% to 10%): Asthenia
Frequency not reported: Fatigue
Postmarketing reports: Malaise, fatigue[Ref]
Rare (less than 0.1%): Rash
Postmarketing reports: Allergic dermatitis, erythema, rash[Ref]
Rare (less than 0.1%): Dysuria[Ref]
Frequency not reported: Urinary retention, impotence in male patients
Postmarketing reports: Suppressed lactation[Ref]
Postmarketing reports: Palpitations, tachyarrhythmias, thrombosis, thrombophlebitis[Ref]
Postmarketing reports: Face edema, angioedema, anaphylactic shock[Ref]
Postmarketing reports: Local pain, edema, skin color change, reflex sympathetic dystrophy syndrome (caused by inadvertent IV injection)[Ref]
Postmarketing reports: Delirium or symptoms of delirium such as amnesia (or transient global amnesia), nervousness, agitation, confusional state, delusion, disorientation, hallucination (including visual hallucination), and mania, mood (altered and pseudodementia).[Ref]
Postmarketing reports: Dyspnea, nasal congestion[Ref]
1. Kagan G, Huddlestone L, Wolstencroft P "Comparison of dicyclomine with antacid and without antacid in dyspepsia." J Int Med Res 12 (1984): 174-8
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. "Product Information. Bentyl (dicyclomine)." Aventis Pharmaceuticals, Kansas City, MO.
Not all side effects for Dibent may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Dibent (dicyclomine)
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