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Dexferrum Side Effects

Generic Name: iron dextran

Note: This document contains side effect information about iron dextran. Some of the dosage forms listed on this page may not apply to the brand name Dexferrum.

For the Consumer

Applies to iron dextran: injection solution

Along with its needed effects, iron dextran (the active ingredient contained in Dexferrum) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking iron dextran:

Incidence Not Known

  • Backache
  • blood in the urine
  • bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • chest pain or discomfort
  • chills
  • cold, clammy skin
  • confusion
  • cough
  • difficulty with moving
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast, slow, pounding, or irregular heartbeat or pulse
  • fast, weak pulse
  • feeling of warmth
  • fever
  • headache
  • hives or welts, itching, or rash
  • lightheadedness, dizziness, or fainting
  • muscle pain or stiffness
  • nausea
  • nervousness
  • no blood pressure or pulse
  • pain in the joints
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the face, neck, arms, and occasionally, upper chest
  • redness of the skin
  • seizures
  • stopping of heart
  • sweating
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • unconsciousness
  • unusual tiredness or weakness
  • vomiting

Some side effects of iron dextran may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence Not Known

  • Abdominal or stomach pain
  • change in taste
  • diarrhea
  • soreness or pain at the injection site

For Healthcare Professionals

Applies to iron dextran: injectable solution

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylactoid reactions (including dyspnea, urticaria, rashes, itching, nausea, and shivering)

Very rare (less than 0.01%): Acute severe anaphylactoid reactions (sudden onset of respiratory difficulty and/or cardiovascular collapse)

Frequency not reported: Anaphylactic reactions, fatal anaphylactic reactions[Ref]

Dermatologic

Uncommon (0.1% to 1%): Flushing, pruritus, rash

Rare (less than 0.1%): Angioedema, sweating

Frequency not reported: Urticaria, purpura[Ref]

Nervous system

Uncommon (0.1% to 1%): Numbness

Rare (less than 0.1%): Loss of consciousness, seizure, dizziness, tremor

Very rare (less than 0.01%): Headache, paresthesia

Frequency not reported: Convulsions, syncope, unresponsiveness, altered taste[Ref]

Musculoskeletal

Uncommon (0.1% to 1%): Cramps

Rare (less than 0.1%): Myalgias

Frequency not reported: Arthralgia, exacerbation of joint pain, arthritis, backache[Ref]

Other

Uncommon (0.1% to 1%): Feeling hot

Rare (0.01% to 0.1%): Fatigue, chest pain

Very rare (less than 0.01%): Transient deafness

Frequency not reported: Fever, weakness, febrile episodes, chills[Ref]

Respiratory

Uncommon (0.1% to 1%): Dyspnea

Frequency not reported: Respiratory arrest, bronchospasm, wheezing[Ref]

Ocular

Uncommon (0.1% to 1%): Blurred vision[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, emesis, abdominal pain

Rare (less than 0.1%): Diarrhea

Frequency not reported: Vomiting[Ref]

Cardiovascular

Rare (0.01 to 0.1%): Arrhythmia, tachycardia, hypotension

Very rare (less than 0.01%): Bradycardia, palpitations, hypertension

Frequency not reported: Chest tightness, shock, cyanosis, cardiac arrest[Ref]

Local

Rare (less than 0.1%): Pain and brown pigmentation at injection site

Frequency not reported: Soreness or inflammation at or near injection site, local phlebitic reaction, staining of the skin, bleeding, formation of sterile abscesses, tissue necrosis, atrophy, pain, sterile abscess, cellulitis[Ref]

Hematologic

Very rare (less than 0.01%): Hemolysis

Frequency not reported: Leukocytosis, lymphadenopathy[Ref]

Psychiatric

Rare (less than 0.1%): Restlessness, mental status changes

Frequency not reported: Disorientation[Ref]

Oncologic

Frequency not reported: Tumors at the injection site[Ref]

Genitourinary

Frequency not reported: Hematuria[Ref]

References

1. "Product Information. DexFerrum (iron dextran)." American Regent Laboratories Inc, Shirley, NY.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. INFeD (iron dextran)." Schein Pharmaceuticals Inc, Florham Park, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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