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Dexferrum Side Effects

Generic Name: iron dextran

Note: This page contains information about the side effects of iron dextran. Some of the dosage forms included on this document may not apply to the brand name Dexferrum.

For the Consumer

Applies to iron dextran: injection solution

In addition to its needed effects, some unwanted effects may be caused by iron dextran (the active ingredient contained in Dexferrum). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking iron dextran, check with your doctor or nurse immediately:

Incidence not known:
  • Backache
  • blood in the urine
  • bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • chest pain or discomfort
  • chills
  • cold, clammy skin
  • confusion
  • cough
  • difficulty with moving
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast, slow, pounding, or irregular heartbeat or pulse
  • fast, weak pulse
  • feeling of warmth
  • fever
  • headache
  • hives or welts, itching, or rash
  • lightheadedness, dizziness, or fainting
  • muscle pain or stiffness
  • nausea
  • nervousness
  • no blood pressure or pulse
  • pain in the joints
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the face, neck, arms, and occasionally, upper chest
  • redness of the skin
  • seizures
  • stopping of heart
  • sweating
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • unconsciousness
  • unusual tiredness or weakness
  • vomiting

Minor Side Effects

Some of the side effects that can occur with iron dextran may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:
  • Abdominal or stomach pain
  • change in taste
  • diarrhea
  • soreness or pain at the injection site

For Healthcare Professionals

Applies to iron dextran: injectable solution

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylactoid reactions (including dyspnea, urticaria, rashes, itching, nausea, and shivering)
Very rare (less than 0.01%): Acute severe anaphylactoid reactions (sudden onset of respiratory difficulty and/or cardiovascular collapse)
Frequency not reported: Anaphylactic reactions, fatal anaphylactic reactions[Ref]

Dermatologic

Uncommon (0.1% to 1%): Flushing, pruritus, rash
Rare (less than 0.1%): Angioedema, sweating
Frequency not reported: Urticaria, purpura[Ref]

Nervous system

Uncommon (0.1% to 1%): Numbness
Rare (less than 0.1%): Loss of consciousness, seizure, dizziness, tremor
Very rare (less than 0.01%): Headache, paresthesia
Frequency not reported: Convulsions, syncope, unresponsiveness, altered taste[Ref]

Musculoskeletal

Uncommon (0.1% to 1%): Cramps
Rare (less than 0.1%): Myalgias
Frequency not reported: Arthralgia, exacerbation of joint pain, arthritis, backache[Ref]

Other

Uncommon (0.1% to 1%): Feeling hot
Rare (0.01% to 0.1%): Fatigue, chest pain
Very rare (less than 0.01%): Transient deafness
Frequency not reported: Fever, weakness, febrile episodes, chills[Ref]

Respiratory

Uncommon (0.1% to 1%): Dyspnea
Frequency not reported: Respiratory arrest, bronchospasm, wheezing[Ref]

Ocular

Uncommon (0.1% to 1%): Blurred vision[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, emesis, abdominal pain
Rare (less than 0.1%): Diarrhea
Frequency not reported: Vomiting[Ref]

Cardiovascular

Rare (0.01 to 0.1%): Arrhythmia, tachycardia, hypotension
Very rare (less than 0.01%): Bradycardia, palpitations, hypertension
Frequency not reported: Chest tightness, shock, cyanosis, cardiac arrest[Ref]

Local

Rare (less than 0.1%): Pain and brown pigmentation at injection site
Frequency not reported: Soreness or inflammation at or near injection site, local phlebitic reaction, staining of the skin, bleeding, formation of sterile abscesses, tissue necrosis, atrophy, pain, sterile abscess, cellulitis[Ref]

Hematologic

Very rare (less than 0.01%): Hemolysis
Frequency not reported: Leukocytosis, lymphadenopathy[Ref]

Psychiatric

Rare (less than 0.1%): Restlessness, mental status changes
Frequency not reported: Disorientation[Ref]

Oncologic

Frequency not reported: Tumors at the injection site[Ref]

Genitourinary

Frequency not reported: Hematuria[Ref]

References

1. "Product Information. DexFerrum (iron dextran)." American Regent Laboratories Inc, Shirley, NY.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. INFeD (iron dextran)." Schein Pharmaceuticals Inc, Florham Park, NJ.

Not all side effects for Dexferrum may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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