Denavir Side Effects

Generic name: penciclovir topical

Medically reviewed by Drugs.com. Last updated on Jul 20, 2023.

Note: This document contains side effect information about penciclovir topical. Some dosage forms listed on this page may not apply to the brand name Denavir.

Applies to penciclovir topical: topical cream.

Serious side effects of Denavir

Along with its needed effects, penciclovir topical (the active ingredient contained in Denavir) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking penciclovir topical:

Rare

• Mild pain, burning, or stinging

Other side effects of Denavir

Some side effects of penciclovir topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Headache

Less common

• Change in sense of taste
• decreased sensitivity of skin, particularly to touch
• redness of the skin
• skin rash

For Healthcare Professionals

Applies to penciclovir topical: topical cream.

General

In clinical trials, 1 or more local side effects were reported by 3% of patients using penciclovir topical (the active ingredient contained in Denavir) and 4% of patients using placebo.^[Ref]

Local

Common (1% to 10%): Application site reaction (including skin burning sensation, skin pain, hypoesthesia)

Frequency not reported: Hypesthesia/local anesthesia, erythematous rash, taste perversion

Dermatologic

Frequency not reported: Mild erythema

Postmarketing reports: Allergic dermatitis (including rash, pruritus, blisters, edema), local edema, pain, paresthesia, pruritus, skin discoloration, urticaria, aggravated condition, decreased therapeutic response^[Ref]

Nervous system

Postmarketing reports: Headache, parosmia^[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity^[Ref]

Other

Postmarketing reports: Oral/pharyngeal edema^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer