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Generic Name: penciclovir topical (pen SYE kloe veer TAH pih kal)
Brand Names: Denavir

What is Denavir?

Denavir is a cream containing antiviral medication.

Denavir is used topically for the treatment of recurrent cold sores on the lips and face, associated with the herpes simplex virus. It works by preventing the herpes simplex virus from growing and should begin applied at the first hint of a developing cold sore./p>

Denavir may also be used for purposes other than those listed in this medication guide.

Important information

Do not apply Denavir to the inside of the nose or in or near the eyes, as it may cause irritation.

For best results, treatment with Denavir should begin as soon as possible after symptoms appear.

Who should not use Denavir?

Denavir is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not use this medication during pregnancy without first talking to your doctor. It is not known whether this medication passes into breast milk. Do not use this medication if you are breast-feeding a baby without first talking to your doctor.

How should I use Denavir?

Use Denavir exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Denavir should be applied to cold sore lesions every 2 hours while awake for a period of four days, unless otherwise directed by your doctor.

Denavir should be used to treat cold sores on the lips and face only.

For best results, treatment with this medication should begin as soon as possible after symptoms appear.

Do not apply Denavir to the inside of the nose or in or near the eyes, as it may cause irritation. Store this medication at room temperature away from moisture and heat.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Use the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and use only your next regularly scheduled dose.

What happens if I overdose?

An overdose of this medication is unlikely to threaten life. If an excessive amount of the cream has been used, or if the cream has been ingested, contact a poison control center or an emergency room for advice.

What should I avoid?

There are no restrictions on food, beverages, or activity during treatment with Denavir, unless otherwise directed by your doctor.

Denavir side effects

Serious side effects have not been reported with the use of Denavir.

Other less serious side effects may be more likely to occur. Continue to use this medication and talk to your doctor if you experience:

  • headache;

  • local numbness or tingling where the cream is applied;

  • changes in taste;

  • rash; or

  • irritation at the application site.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

See also: Side effects (in more detail)

What other drugs will affect Denavir?

Do not use other topical medications to treat the same area at them same time as Denavir, unless otherwise directed by your doctor.

No other medicines have been reported to interact with Denavir. Talk to your doctor or pharmacist before taking other prescription or over-the-counter medications during treatment with this medication.

Where can I get more information?

  • Your pharmacist has additional information about Denavir written for health professionals that you may read.

What does Denavir look like?

Penciclovir topical is available with a prescription under the brand name Denavir in a 1% cream formulation. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2017 Cerner Multum, Inc. Version: 1.03. Revision Date: 2/13/04 4:06:38 PM.