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Cerezyme Side Effects

Generic name: imiglucerase

Medically reviewed by Drugs.com. Last updated on Sep 30, 2024.

Note: This document provides detailed information about Cerezyme.

Applies to imiglucerase: intravenous powder for solution Side Effects associated with imiglucerase. Some dosage forms listed on this page may not apply specifically to the brand name Cerezyme.

Applies to imiglucerase: intravenous powder for solution.

Precautions

It is very important that your doctor check your or your child's progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Tell your doctor if you are pregnant or planning to become pregnant before receiving this medicine.

This medicine may cause serious allergic reactions, including anaphylaxis and infusion-related reactions, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have back pain, chest tightness, cough, difficulty swallowing, dizziness, fast heartbeat, flushing, hives, itching, skin rash, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, nausea and vomiting, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, trouble breathing, or unusual tiredness or weakness.

Serious side effects of Cerezyme

Along with its needed effects, imiglucerase (the active ingredient contained in Cerezyme) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking imiglucerase:

Incidence not known

  • bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • chest pain, discomfort, or tightness
  • confusion
  • cough
  • difficulty swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • feeling of warmth
  • fever or chills
  • headache
  • hives, itching, skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the face, neck, arms and occasionally, upper chest
  • sneezing
  • sore throat
  • sweating
  • trouble breathing
  • unusual tiredness or weakness

Other side effects of Cerezyme

Some side effects of imiglucerase may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • back pain
  • diarrhea
  • nausea
  • stomach pain
  • vomiting

For healthcare professionals

Applies to imiglucerase: intravenous powder for injection.

General adverse events

Experience in patients treated with this drug have revealed that about 13.8% of patients experienced adverse events which were judged to be related to administration and included discomfort, pruritus, burning, swelling, or sterile abscess at the site of venipuncture.[Ref]

Local

Gastrointestinal

Cardiovascular

Immunologic

Dermatologic

Musculoskeletal

Respiratory

Nervous system

Other

See also:

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2008) "Product Information. Cerezyme (imiglucerase)." Genzyme Corporation

Further information

Cerezyme side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.