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Cepastat Sore Throat & Cough Side Effects

Generic name: benzocaine / dextromethorphan / menthol topical

Note: This document contains side effect information about benzocaine / dextromethorphan / menthol topical. Some dosage forms listed on this page may not apply to the brand name Cepastat Sore Throat & Cough.

Applies to benzocaine/dextromethorphan/menthol topical: mucous membrane lozenge.



Frequency not reported: Angioedema


Rare (less than 0.1%): Fixed-drug eruptions

Frequency not reported: Angioedema[Ref]



Frequency not reported: Contact dermatitis, urticaria


Frequency not reported: Pruritus, rash, urticaria[Ref]



Frequency not reported: Burning, stinging


Frequency not reported: Application site redness/irritation[Ref]



Frequency not reported: Abdominal pain, diarrhea, gastrointestinal disturbance, nausea, upset stomach, vomiting[Ref]



Frequency not reported: Abuse, excitation, insomnia, mental confusion[Ref]

Nervous system


Frequency not reported: Convulsions, dizziness, drowsiness[Ref]



Postmarketing reports: Methemoglobinemia[Ref]



Frequency not reported: Respiratory depression[Ref]



Frequency not reported: Edema[Ref]

More about Cepastat Sore Throat & Cough (benzocaine / dextromethorphan / menthol topical)

Related treatment guides


1. Stubb S, Reitamo S (1990) "Fixed-drug eruption due to dextromethorphan ." Arch Dermatol, 126, p. 970-1

2. Hall RC, Beresford TP, Stickney SK, Nasdahl CS, Coleman JH (1985) "Psychiatric reactions produced by respiratory drugs." Psychosomatics, 26, 605-8,616-7

3. Helfer J, Kim OM (1990) "Psychoactive abuse potential of Robitussin-DM." Am J Psychiatry, 147, p. 672-3

4. Murray S, Brewerton T (1993) "Abuse of over-the-counter dextromethorphan by teenagers." South Med J, 86, p. 1151-3

5. Wolfe TR, Caravati EM (1995) "Massive dextromethorphan ingestion and abuse." Am J Emerg Med, 13, p. 174-6

6. Polles A, Griffith JL (1996) "Dextromethorphan-induced mania." Psychosomatics, 37, p. 71-4

7. Bostwick JM (1996) "Dextromethorphan-induced manic symptoms in a bipolar patient on lithium." Psychosomatics, 37, p. 571-2

8. Knowles SR, Weber E (1998) "Dextromethorphan anaphylaxis." J Allerg Clin Immunol, 102, p. 316-7

9. (2003) "Product Information. Stopain (menthol topical)." DRJ Group Inc

10. "Product Information. Cold and Hot (menthol topical)." Major Pharmaceuticals Inc

11. (2004) "Product Information. BENGAY Pain Relieving (menthol topical)." Pfizer U.S. Pharmaceuticals Group

12. (2005) "Product Information. Solarcaine Plus Aloe (benzocaine topical)." Schering-Plough Healthcare Products

13. (2005) "Product Information. Americaine Hemorrhoidal (benzocaine topical)." Novartis Consumer Health

14. (2005) "Product Information. Dermoplast (benzocaine topical)." MedTech Inc

15. (2005) "Product Information. Outgro Pain Relief (benzocaine topical)." MedTech Inc

16. (2005) "Product Information. Cepacol Lozenges (cetylpyridinium topical)." GlaxoSmithKline Inc

17. (2005) "Product Information. Chloraseptic (benzocaine topical)." Procter and Gamble Pharmaceuticals

18. (2005) "Product Information. Vagisil Feminine Cream (benzocaine topical)." Combe Inc

19. (2005) "Product Information. Lanacane (benzocaine topical)." Combe Inc

20. (2005) "Product Information. Hurricaine (benzocaine topical)." Beutlich

21. Cerner Multum, Inc. "UK Summary of Product Characteristics."

22. Throm MJ, Stevens MD, Hansen C (2007) "Benzocaine-induced methemoglobinemia in two patients: interdisciplinary collaboration, management, and near misses." Pharmacotherapy, 27, p. 1206-14

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.