Carteolol Side Effects
For the Consumer
Applies to carteolol: oral tablet
Get emergency medical help if you have any of these signs of an allergic reaction while taking carteolol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
slow or uneven heartbeats;
feeling light-headed, fainting;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
cold feeling in your hands and feet.
Less serious side effects of carteolol may include:
decreased sex drive, impotence, or difficulty having an orgasm;
sleep problems (insomnia);
tired feeling; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to carteolol: oral tablet
Carteolol is generally well-tolerated. Side effects are usually mild and transient.[Ref]
Nervous system side effects include headache in up to 1% to 17%, asthenia in 8%, insomnia in 5%, dizziness in 8%, paresthesias in 2%, and vertigo, nervousness, headache or fatigue in 1% of patients.[Ref]
Cardiovascular problems include chest pain in 2% and edema in 1% of patients. Carteolol may cause or worsen AV heart block. In the rare cases of new or worsened congestive heart failure that are associated with carteolol, a cause-and-effect relationship is not established.[Ref]
The etiology of "chest pain" was not described in studies and reviews from the medical literature.[Ref]
Gastrointestinal complaints of abdominal or epigastric pain in 1% to 7% and diarrhea or nausea in 2% of patients is reported.[Ref]
Respiratory side effects are rare. Cough, pharyngitis, or sinusitis are reported in 1% to 5% of patients. Dyspnea is reported rarely. Patients with a history of reactive airways disease may be more likely to become short of breath while taking carteolol, as during therapy with any beta-blocker.[Ref]
Musculoskeletal pain is reported in approximately 3% to 13% of patients.[Ref]
Carteolol and pindolol, beta-adrenergic receptor antagonists with intrinsic sympathomimetic activity (ISA), have more commonly been associated with muscle cramps and elevated serum creatine phosphokinase (CK) levels than beta-blockers without ISA.[Ref]
Genitourinary complaints of impotence are reported in less than 1% of male patients.[Ref]
Psychiatric side effects including reports of depression have been associated with carteolol.[Ref]
1. "Multum Information Services, Inc. Expert Review Panel"
2. Frishman WH, Covey S "Penbutolol and carteolol: two new beta-adrenergic blockers with partial agonism." J Clin Pharmacol 30 (1990): 412-21
3. Simon H, Schuppan U "The treatment of angina pectoris with the new beta-receptor blocker carteolol. Results of a controlled trial in comparison with pindolol." Arzneimittelforschung 33 (1983): 318-21
4. Luther RR, Glassman HN, Jordan DC "A comparison of carteolol and nadolol in the treatment of stable angina pectoris." J Clin Pharmacol 28 (1988): 634-9
5. Tarkiainen A, Saraste K, Seppala T, Gordin A, Auvinen J "A controlled study of the antihypertensive effect of carteolol, a new beta-adrenergic receptor blocking drug, in combination with hydrochlorothiazide and amiloride." Eur J Clin Pharmacol 19 (1981): 239-44
6. Luther RR, Maurath CJ, Klepper MJ, Peckinpaugh RO, Ringham GL "Carteolol treatment of essential hypertension: a long-term study of safety and efficacy." J Int Med Res 14 (1986): 175-84
7. Velasquez MT, Byrne D, Hoffmann RG "Antihypertensive effect of carteolol in thiazide-treated hypertensive subjects." J Clin Pharmacol 25 (1985): 601-6
8. Luther RR, Glassman HN, Jordan DC, Klepper MJ "Long-term treatment of angina pectoris with carteolol: a new beta-adrenergic receptor blocking agent." J Int Med Res 14 (1986): 167-74
9. "Carteolol and penbutolol for hypertension." Med Lett Drugs Ther 31 (1989): 70-1
10. Imai Y, Watanabe N, Hashimoto J, Nishiyama A, Sakuma H, Sekino H, Omata K, Abe K "Muscle cramps and elevated serum creatine phosphokinase levels induced by beta-adrenoceptor blockers." Eur J Clin Pharmacol 48 (1995): 29-34
Not all side effects for carteolol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about carteolol
- Other brands: Cartrol
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