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Butalbital Side Effects

Applies to butalbital: compounding powder

Nervous system

Nervous system side effects including drowsiness, lightheadedness, dizziness, sedation, and an intoxicated feeling have been reported frequently from the use of butalbital. Headache and seizures have been reported infrequently. Mental confusion, excitement, or depression have also been reported due to either intolerance (primarily in elderly or debilitated patients) or due to an overdosage of butalbital.[Ref]


Gastrointestinal side effects including nausea, vomiting, and abdominal pain have been reported frequently with the use of butalbital.[Ref]


Respiratory side effects including dyspnea have been reported frequently with the use of butalbital.[Ref]


1. "Product Information. Sedapap (acetaminophen-butalbital)" Merz Pharmaceuticals, Greensboro, NC.

2. "Product Information. Fiorinal (ASA/butalbital/caffeine)" Actavis (formerly Abrika Pharmaceuticals LLP), Sunrise, FL.

3. "Product Information. Fioricet with Codeine Capsules (APAP/butalbital/caffeine/codeine)" Novartis Pharmaceuticals, East Hanover, NJ.

4. "Product Information. Fiorinal with Codeine Capsules (ASA/butalbital/caffeine/codeine)" Novartis Pharmaceuticals, East Hanover, NJ.

5. "Product Information. Fioricet (APAP/butalbital/caffeine)." Novartis Pharmaceuticals, East Hanover, NJ.

6. "Product Information. Esgic-plus (APAP/butalbital/caffeine)" Forest Pharmaceuticals, St. Louis, MO.

Some side effects of butalbital may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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