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Bexxar Dosimetric Side Effects

Generic name: tositumomab

Note: This document contains side effect information about tositumomab. Some of the dosage forms listed on this page may not apply to the brand name Bexxar Dosimetric.

Applies to tositumomab: intravenous kit


Common (1% to 10%): Hypotension, vasodilation[Ref]


Very common (10% or more): Rash, pruritus

Common (1% to 10%): Sweating[Ref]


Common (1% to 10%): Hypothyroidism[Ref]


Very common (10% or more): Abdominal pain, nausea, vomiting, diarrhea, anorexia

Common (1% to 10%): Constipation, dyspepsia[Ref]


Very common (10% or more): Neutropenia, thrombocytopenia, anemia[Ref]


Common (1% to 10%): Allergic (hypersensitivity) reactions (allergic reaction, facial edema, injection site hypersensitivity, anaphylactic reaction, laryngismus, serum sickness)

Postmarketing reports: Hypersensitivity reactions including fatal anaphylaxis[Ref]


Very common (10% or more): Positive serology for human anti-mouse antibodies (HAMA)[Ref]


Frequency not reported: Infusion reactions[Ref]


Common (1% to 10%): Peripheral edema, weight loss[Ref]


Very common (10% or more): Myalgia, arthralgia

Common (1% to 10%): Back pain, neck pain[Ref]

Nervous system

Common (1% to 10%): Dizziness, somnolence

Postmarketing reports: Axonal neuropathy leading to quadriparesis[Ref]


Common (1% to 10%): Secondary malignancies (non-melanoma skin, colorectal, head and neck, breast, lung, bladder, melanoma, gastric)

Frequency not reported: Secondary leukemia, myelodysplastic syndrome[Ref]


Very common (10% or more): Asthenia, fever, infections, pain, chills, headache

Common (1% to 10%): Chest pain, serious infections (pneumonia, bacteremia, septicemia, bronchitis, skin infections)[Ref]


Very common (10% or more): Cough, pharyngitis, dyspnea, rhinitis

Common (1% to 10%): Pneumonia[Ref]


1. "Product Information. Bexxar I 131 Therapeutic (iodine I 131 tositumomab)." GlaxoSmithKline, Research Triangle Park, NC.

2. "Product Information. BexxarTherapy (tositumomab)." GlaxoSmithKline Inc, Oakville, IA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.