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Betagan C-Cap Side Effects

Generic Name: levobunolol ophthalmic

Note: This document contains side effect information about levobunolol ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Betagan C-Cap.

For the Consumer

Applies to levobunolol ophthalmic: ophthalmic solution

Along with its needed effects, levobunolol ophthalmic (the active ingredient contained in Betagan C-Cap) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking levobunolol ophthalmic:

More common
  • Burning or stinging in eye
  • drainage from the eye
  • redness, swelling, and/or itching of eye and eyelid
Less common
  • Blurred vision
  • chest pain or discomfort
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • shortness of breath
  • slow or irregular heartbeat
  • sweating
  • unusual tiredness or weakness
Rare
  • Eye pain
  • headache
  • hives or welts
  • itching skin
  • redness of skin
  • shakiness and unsteady walk
  • skin rash
  • tearing
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual drowsiness, dullness, or feeling of sluggishness
Incidence not determined
  • Blistering, peeling, loosening of skin
  • blue lips, fingernails, or skin
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chills
  • cough
  • decreased urine output
  • diarrhea
  • difficult or labored breathing
  • difficulty in chewing, swallowing, or talking
  • dilated neck veins
  • disturbed color perception
  • double vision
  • drooping eyelids
  • extreme fatigue
  • fast, pounding, or racing heartbeat or pulse
  • fever
  • halos around lights
  • hoarseness
  • inability to speak
  • irregular, fast or slow, or shallow breathing
  • irritation
  • joint pain, stiffness, or swelling
  • muscle pain
  • muscle weakness
  • night blindness
  • no blood pressure or pulse
  • noisy breathing
  • overbright appearance of lights
  • red skin lesions, often with a purple center
  • seeing double
  • seizures
  • severe numbness, especially on one side of the face or body
  • severe or sudden headache
  • severe tiredness
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots in mouth or on lips
  • stopping of heart
  • swelling of eyelids, face, lips, hands, fingers, feet, or lower legs
  • temporary blindness
  • tightness in chest
  • troubled breathing
  • tunnel vision
  • unconsciousness
  • weakness in arm and/or leg on one side of the body, sudden and severe
  • weight gain
  • wheezing

Some side effects of levobunolol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined
  • Decreased interest in sexual intercourse
  • discouragement
  • feeling sad or empty
  • inability to have or keep an erection
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss in sexual ability, desire, drive, or performance
  • loss of interest or pleasure
  • nausea
  • stuffy nose
  • tiredness
  • trouble concentrating
  • trouble sleeping

For Healthcare Professionals

Applies to levobunolol ophthalmic: ophthalmic solution

General

The most commonly reported side effects were ocular burning/stinging, blepharoconjunctivitis, eye irritation, and eye pain.[Ref]

Ocular

Very common (10% or more): Eye irritation, eye pain
Common (1% to 10%): Blepharitis, conjunctivitis
Rare (less than 0.1%): Iridocyclitis
Frequency not reported: Conjunctival/ocular hyperemia, allergic conjunctivitis, decreased corneal reflex, keratitis, blurred vision, punctate keratitis, eye/eyelids pruritus, eye/eyelid edema, eye discharge, increased lacrimation, dry eye, choroidal detachment following filtration surgery, corneal erosion, diplopia, ptosis, corneal calcification, decreased corneal sensitivity, blepharoptosis[Ref]

Respiratory

Frequency not reported: Asthma, dyspnea, throat irritation, nasal discomfort, bronchospasm (predominantly in patients with pre-existing bronchospastic disease), cough, respiratory failure, nasal congestion[Ref]

Cardiovascular

Frequency not reported: Raynaud's phenomenon, syncope, bradycardia, atrioventricular block, palpitations, hypotension, arrhythmia, cardiac arrest, cardiac failure, chest pain, congestive heart failure, cold hands and feet[Ref]

Hypersensitivity

Frequency not reported: Anaphylactic reaction, systemic allergic reactions including angioedema[Ref]

Nervous system

Rare (less than 0.1%): Transient ataxia
Frequency not reported: Confusion, dizziness, somnolence, lethargy, headache, memory loss, cerebral ischemia, cerebrovascular accident, increases in signs and symptoms of myasthenia gravis, paresthesia, dysgeusia[Ref]

Gastrointestinal

Frequency not reported: Nausea, abdominal pain, diarrhea, dry mouth, dyspepsia, vomiting[Ref]

Genitourinary

Frequency not reported: Decreased libido, sexual dysfunction, impotence[Ref]

Musculoskeletal

Frequency not reported: Myalgia[Ref]

Psychiatric

Frequency not reported: Depression, insomnia, nightmares[Ref]

Other

Frequency not reported: Edema, fatigue, asthenia[Ref]

Dermatologic

Frequency not reported: Stevens-Johnson syndrome, urticaria, contact dermatitis (including allergic contact dermatitis), rash, skin exfoliation, lichenoid keratosis, pruritus, erythema of eyelid, eyelid eczema, alopecia, psoriasiform rash, exacerbation of psoriasis[Ref]

Metabolic

Frequency not reported: Hypoglycemia, masked symptoms of hypoglycemia in insulin-dependent diabetics[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Betagan Liquifilm (levobunolol)." Allergan Inc, Irvine, CA.

Some side effects of Betagan C-Cap may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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