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Asthmanefrin Side Effects

Generic Name: racepinephrine

Note: This page contains information about the side effects of racepinephrine. Some of the dosage forms included on this document may not apply to the brand name Asthmanefrin.

For the Consumer

Applies to racepinephrine: inhalation solution

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; loss of appetite; nausea; nervousness; tremors; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur while taking racepinephrine (the active ingredient contained in Asthmanefrin)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast heartbeat; wheezing.

For Healthcare Professionals

Applies to racepinephrine: inhalation solution


Cardiovascular side effects have included elevations of heart rate and blood pressure. In smaller doses, racepinephrine (the active ingredient contained in Asthmanefrin) has caused peripheral coronary arterial vasodilation, but in larger doses, racepinephrine has caused diffuse vasoconstriction. This has caused increased peripheral vascular resistance, which was important in patients with coronary artery disease (worsened myocardial ischemia/angina) or hypertension (risk of emergent hypertension/stroke).

Arrhythmias, including fatal ventricular fibrillation, have been reported in patients with underlying cardiac disease. Rapid rises in blood pressure have produced cerebral hemorrhage, particularly in elderly patients with cardiovascular disease. Angina may occur in patients with coronary artery disease.[Ref]


Gastrointestinal side effects have included nausea and vomiting.[Ref]

Nervous system

Nervous system side effects have included fear, agitation, anxiety, tenseness, restlessness, headache, tremor, dizziness, lightheadedness, nervousness, sleeplessness, excitability, weakness, and increased parkinsonian tremors.[Ref]


Psychiatric side effects have included agitation, disorientation, impaired memory, aggressive or assautive behavior, hallucinations, and psychosis.


1. "Product Information. S2 Inhalant (racepinephrine)." Nephron Pharmaceuticals, Orlando, FL.

Not all side effects for Asthmanefrin may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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