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Anectine Side Effects

Generic Name: succinylcholine

Note: This document contains side effect information about succinylcholine. Some of the dosage forms listed on this page may not apply to the brand name Anectine.

For the Consumer

Applies to succinylcholine: parenteral injection

Side effects include:

Various degrees of skeletal muscle weakness.

For Healthcare Professionals

Applies to succinylcholine: compounding powder, injectable powder for injection, injectable solution, intravenous solution

Hypersensitivity

Very rare (less than 0.01%): Anaphylaxis[Ref]

Musculoskeletal

Very common (10% or more): Muscle fasciculation, post-operative muscle pain

Common (1% to 10%): Myoglobinemia, myoglobinuria

Rare (less than 0.1%): Trismus

Frequency not reported: Rhabdomyolysis, myoglobinuria, myoglobinemia, elevated creatine phosphokinase, hypertonia, precipitation or exacerbation of myasthenia gravis[Ref]

Ocular

Common (1% to 10%): Increased intraocular pressure[Ref]

Metabolic

Common (1% to 10%): Hyperkalemia[Ref]

Respiratory

Rare (0.01% to 0.1%): Bronchospasm, prolonged respiratory depression, apnea

Very rare (less than 0.01%): Increased bronchial secretions, pulmonary edema (in infants)[Ref]

Other

Very rare (less than 0.01%): Malignant hyperthermia, porphyria[Ref]

Renal

Frequency not reported: Renal failure[Ref]

Cardiovascular

Common (1% to 10%): Bradycardia, tachycardia, flushing, hypertension, hypotension

Rare (less than 0.1%): Arrhythmias (including ventricular arrhythmia), cardiac arrest, hyperkalemia-related cardiac arrest (following administration to patients with congenital cerebral palsy, tetanus, Duchenne muscular dystrophy, and closed head injury)

Frequency not reported: Circulatory collapse, shock[Ref]

Dermatologic

Common (1% to 10%): Rash[Ref]

Gastrointestinal

Very common (10% or more): Increased intragastric pressure, excessive salivation

Frequency not reported: Increased bowel movements, increased gastric secretions[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Quelicin Chloride (succinylcholine)." Abbott Pharmaceutical, Abbott Park, IL.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

4. "Product Information. Anectine (succinylcholine)." Glaxo Wellcome, Research Triangle Park, NC.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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