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Anectine Flo-Pack Side Effects

Generic name: succinylcholine

Medically reviewed by Last updated on Oct 12, 2022.

Note: This document contains side effect information about succinylcholine. Some dosage forms listed on this page may not apply to the brand name Anectine Flo-Pack.

Applies to succinylcholine: parenteral injection.


    Rhabdomyolysis with Hyperkalemia
  • Risk of acute rhabdomyolysis with hyperkalemia followed by ventricular arrhythmias, cardiac arrest, and death in apparently healthy children and adolescents who subsequently were found to have undiagnosed skeletal muscle myopathy (e.g., Duchenne‚Äôs muscular dystrophy).100

  • Use in children and adolescents should be reserved for those undergoing emergency intubation, those in whom an airway should be secured immediately (e.g., patients with laryngospasm, difficult airway, or full stomach), or those in whom a suitable vein is not accessible and IM administration is needed.100 (See Pediatric Use under Cautions.)

Side effects include:

Various degrees of skeletal muscle weakness.

For Healthcare Professionals

Applies to succinylcholine: compounding powder, injectable powder for injection, injectable solution, intravenous solution.


Very rare (less than 0.01%): Anaphylaxis[Ref]


Very common (10% or more): Muscle fasciculation, post-operative muscle pain

Common (1% to 10%): Myoglobinemia, myoglobinuria

Rare (less than 0.1%): Trismus

Frequency not reported: Rhabdomyolysis, myoglobinuria, myoglobinemia, elevated creatine phosphokinase, hypertonia, precipitation or exacerbation of myasthenia gravis[Ref]


Common (1% to 10%): Increased intraocular pressure[Ref]


Common (1% to 10%): Hyperkalemia[Ref]


Rare (0.01% to 0.1%): Bronchospasm, prolonged respiratory depression, apnea

Very rare (less than 0.01%): Increased bronchial secretions, pulmonary edema (in infants)[Ref]


Very rare (less than 0.01%): Malignant hyperthermia, porphyria[Ref]


Frequency not reported: Renal failure[Ref]


Common (1% to 10%): Bradycardia, tachycardia, flushing, hypertension, hypotension

Rare (less than 0.1%): Arrhythmias (including ventricular arrhythmia), cardiac arrest, hyperkalemia-related cardiac arrest (following administration to patients with congenital cerebral palsy, tetanus, Duchenne muscular dystrophy, and closed head injury)

Frequency not reported: Circulatory collapse, shock[Ref]


Common (1% to 10%): Rash[Ref]


Very common (10% or more): Increased intragastric pressure, excessive salivation

Frequency not reported: Increased bowel movements, increased gastric secretions[Ref]

More about Anectine Flo-Pack (succinylcholine)

Patient resources

Other brands


Professional resources

Other formulations

Related treatment guides


1. "Product Information. Anectine (succinylcholine)." Glaxo Wellcome (2001):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Quelicin Chloride (succinylcholine)." Abbott Pharmaceutical (2017):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.