Skip to Content

Alka-Seltzer Plus Cold Formula Orange Zest Effervescent Tablets Side Effects

Generic Name: aspirin / chlorpheniramine / phenylephrine

Note: This document contains side effect information about aspirin / chlorpheniramine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Alka-Seltzer Plus Cold Formula Orange Zest Effervescent Tablets.

Applies to aspirin / chlorpheniramine / phenylephrine: oral tablet effervescent

Get emergency medical help if you have any of these signs of an allergic reaction while taking aspirin / chlorpheniramine / phenylephrine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • chest pain, rapid pulse, fast or uneven heart rate;

  • ringing in your ears, severe headache, confusion, hallucinations, severe nervousness, feeling like you might pass out;

  • tremor, seizure (convulsions);

  • feeling short of breath, little or no urinating;

  • redness or swelling, new cold or flu symptoms;

  • easy bruising or bleeding, unusual weakness; or

  • dangerously high blood pressure (severe headache, buzzing in your ears, anxiety, shortness of breath).

Common side effects may include:

  • dizziness, drowsiness, blurred vision;

  • dry mouth, nose, or throat;

  • heartburn, nausea, diarrhea, constipation, upset stomach;

  • feeling nervous, restless, or irritable; or

  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Some side effects of Alka-Seltzer Plus Cold Formula Orange Zest Effervescent Tablets may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Alka-Seltzer Plus Cold Formula Orange Zest Effervescent Tablets (aspirin / chlorpheniramine / phenylephrine)

Consumer resources

Other brands: Alka-Seltzer Plus Cold Formula Sparkling Original Effervescent Tablets

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide