Akineton HCl Side Effects
Generic name: biperiden
Medically reviewed by Drugs.com. Last updated on Dec 23, 2024.
Note: This document provides detailed information about Akineton HCl Side Effects associated with biperiden. Some dosage forms listed on this page may not apply specifically to the brand name Akineton HCl.
Applies to biperiden: oral tablet.
Important warnings
This medicine can cause some serious health issues
Use caution when driving, operating machinery, or performing other hazardous activities.
Biperiden may cause dizziness or blurred vision.
If you experience dizziness or blurred vision, avoid these activities.
Use alcohol cautiously.
Alcohol may increase drowsiness and dizziness while you are taking biperiden.
Avoid becoming overheated.
Biperiden may cause decreased sweating.
This could lead to heat stroke in hot weather or with vigorous exercise.
If you experience any of the following serious side effects, stop taking biperiden (the active ingredient contained in Akineton HCl) and seek emergency medical attention:
-
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
-
unusual fever;
-
fast or irregular heartbeat;
-
anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness;
-
seizures;
-
a rash; or
-
eye pain.
Other, less serious side effects may be more likely to occur. Continue to take biperiden and talk to your doctor if you experience
-
a dry mouth;
-
large pupils or blurred vision;
-
drowsiness;
-
difficulty urinating or constipation;
-
nervousness or anxiety;
-
upset stomach; or
-
decreased sweating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
For healthcare professionals
Applies to biperiden: oral tablet.
Nervous system adverse events
Nervous system side effects have included drowsiness, choreic movements, reduced rapid eye movement sleep, and anticholinergic syndrome. Symptoms of central anticholinergic syndrome include: dilated, sluggish pupils; warm, dry skin; flushing; decreased respiratory tract secretions; foul breath; increased body temperature; decrease bowel sounds; urinary retention; tachycardia/cardiac arrhythmias;delirium, disorientation, anxiety, hallucinations, confusion, incoherence; agitation; hyperactivity, ataxia, loss of memory; paranoia; combativeness and seizures. Central anticholinergic syndrome may progress to stupor, coma, paralysis, cardiac/respiratory arrest and death. Orthostatic dizziness, hypokinesia, and headache have also been reported.[Ref]
A case of choreic movements was reported in a patient on concomitant therapy of biperiden and carbidopa/levodopa.[Ref]
Gastrointestinal
Gastrointestinal side effects have included dry mouth, constipation, gastric irritation, nausea, vomiting, and increased salivation.[Ref]
Psychiatric
Psychiatric side effects have included euphoria, disorientation, agitation, disturbed behavior, and concentration difficulties.[Ref]
Other
Other side effects have included asthenia.[Ref]
Hypersensitivity
Hypersensitivity side effects have included allergic skin reactions.[Ref]
Genitourinary
Genitourinary side effects have included urinary retention.[Ref]
Ocular
Ocular side effects have included blurred vision.[Ref]
Cardiovascular
Cardiovascular side effects have included postural hypotension and bradycardia when administered parenterally.[Ref]
Postural hypotension and bradycardia may be minimized or eliminated by slow intravenous administration.[Ref]
References
1. (2008) "Product Information. Akineton HCl (biperiden)." Par Pharmaceutical Inc
2. Baskak B, Atbasoglu EC, Ozguven HD, Saka MC, Gogus AK (2007) "The effectiveness of intramuscular biperiden in acute akathisia: a double-blind, randomized, placebo-controlled study." J Clin Psychopharmacol, 27, p. 289-94
More about Akineton HCl (biperiden)
- Check interactions
- Compare alternatives
- Drug images
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiparkinson agents
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
Further information
Akineton HCl side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.