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Aerobid-M Side Effects

Generic name: flunisolide

Medically reviewed by Last updated on Sep 11, 2022.

Note: This document contains side effect information about flunisolide. Some dosage forms listed on this page may not apply to the brand name Aerobid-M.

Applies to flunisolide: inhalation aerosol powder.

Serious side effects of Aerobid-M

Along with its needed effects, flunisolide (the active ingredient contained in Aerobid-M) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking flunisolide:

More common

  • Body aches or pain
  • congestion
  • cough
  • dryness or soreness of the throat
  • fever
  • headache
  • hoarseness
  • pain or tenderness around the eyes and cheekbones
  • shortness of breath or troubled breathing
  • sneezing
  • stuffy or runny nose
  • tender, swollen glands in the neck
  • tightness of the chest or wheezing
  • trouble with swallowing
  • voice changes

Less common

  • Bladder pain
  • blistering, peeling, or loosening of the skin
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody nose
  • bloody or cloudy urine
  • blurred vision
  • chest pain
  • chills
  • cough producing mucus
  • diarrhea
  • difficult, burning, or painful urination
  • dizziness
  • fast, irregular, pounding, or racing heartbeat or pulse
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • hives
  • itching
  • joint or muscle pain
  • lower back or side pain
  • nervousness
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid weight gain
  • red, irritated eyes
  • skin rash
  • slow heartbeat
  • sore mouth or tongue
  • sores, ulcers, or white spots in the mouth or on the lips
  • sweating
  • swelling
  • tingling of the hands or feet
  • unusual tiredness or weakness
  • unusual weight gain or loss

Incidence not known

  • Creamy white, curd-like patches in the mouth or throat
  • darkening of the skin
  • discouragement
  • fainting
  • feeling sad or empty
  • irritability
  • loss of appetite
  • loss of interest or pleasure
  • loss of strength or energy
  • muscle weakness
  • nausea
  • pain when eating or swallowing
  • trouble concentrating
  • trouble sleeping
  • vomiting

Other side effects of Aerobid-M

Some side effects of flunisolide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Abdominal or stomach fullness
  • acid or sour stomach
  • appetite changes
  • bad, unusual, or unpleasant (after) taste
  • belching
  • blemishes on the skin
  • burning, dry, or itching eyes
  • change in taste
  • constipation
  • cramps
  • difficulty with moving
  • discharge or excessive tearing
  • dizziness or lightheadedness
  • ear pain
  • fear
  • feeling of constant movement of self or surroundings
  • gas
  • headache, severe and throbbing
  • heartburn
  • heavy bleeding
  • indigestion
  • irritability
  • itching of the vagina or genital area
  • loss of smell or taste
  • muscle aching or cramping
  • muscle stiffness
  • pain during sexual intercourse
  • pain in the neck
  • pimples
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • restlessness
  • sensation of spinning
  • shakiness
  • skin rash, encrusted, scaly, and oozing
  • stomach discomfort, upset, or pain
  • swollen joints
  • thick, white vaginal discharge with no odor or with a mild odor
  • trouble sitting still
  • trouble sleeping
  • upset stomach

For Healthcare Professionals

Applies to flunisolide: compounding powder, inhalation aerosol, inhalation aerosol with adapter.


The most commonly reported adverse reactions include pharyngitis, rhinitis, headache, sinusitis, and increased cough.[Ref]


Very common (10% or more): Pharyngitis (up to 17.5%), rhinitis (up to 15.7%)

Common (1% to 10%): Increased cough, sinusitis, epistaxis, bronchitis, laryngitis, voice alteration, cold symptoms, nasal congestion, sinus drainage, sinus infection, sneezing, sputum, wheezing, bronchospasm, dyspnea, head stuffiness, nasal irritation, sinus discomfort, sore throat, dry throat[Ref]


Common (1% to 10%): Vomiting, dyspepsia, abdominal pain, diarrhea, gastroenteritis, nausea, oral moniliasis, upset stomach, heartburn, constipation, gas, abdominal fullness, glossitis, mouth irritation, phlegm[Ref]

Nervous system

Very common (10% or more): Headache (up to 13.8%)

Common (1% to 10%): Migraine, taste perversion, weakness, numbness, hyperactivity[Ref]


Common (1% to 10%): Neck pain, myalgia

Frequency not reported: Decreased bone mineral density; reduction in growth velocity[Ref]


Common (1% to 10%): Blurred vision, eye discomfort, eye infection

Frequency not reported: Glaucoma, increased intraocular pressure, cataracts[Ref]


Common (1% to 10%): Erythema multiforme, sweating, eczema, pruritus, acne, urticaria


Common (1% to 10%): Chest pain, edema, palpitations, tachycardia, hypertension[Ref]


Common (1% to 10%): Urinary tract infection, dysmenorrhea, vaginitis[Ref]


Common (1% to 10%): Enlarged lymph nodes, capillary fragility[Ref]


Common (1% to 10%): Allergic reaction[Ref]


Common (1% to 10%): Decreased appetite, increased appetite, weight gain[Ref]


Common (1% to 10%): Ear pain, chills, malaise, vertigo, fatigue, loss of smell, ear infection[Ref]


Common (1% to 10%): Insomnia, irritability, shakiness, anxiety, depression, moodiness, hypoactivity[Ref]

More about Aerobid-M (flunisolide)

Patient resources

Other brands

Aerobid, Aerospan HFA

Professional resources

Related treatment guides


1. "Product Information. Aerospan (flunisolide)." Meda Pharmaceuticals (2016):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.