Adenocard Side Effects

Generic name: adenosine

Medically reviewed by Drugs.com. Last updated on Jan 24, 2025.

Note: This document provides detailed information about Adenocard.

Applies to adenosine: intravenous solution Side Effects associated with adenosine. Some dosage forms listed on this page may not apply specifically to the brand name Adenocard.

Applies to adenosine: intravenous solution.

Precautions

It is very important that your doctor check your progress very closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

Heart attack and death may occur after receiving this medicine. Make sure your doctor knows if you have any heart problems (eg, unstable angina or cardiovascular instability) before you have a heart stress test. Check with your doctor right away if you have chest pain or discomfort, nausea, pain or discomfort in arms, jaw, back or neck, sweating, or vomiting.

Do not take anything that contains caffeine before you receive this medicine. This includes medicines, foods, and beverages with caffeine, such as coffee, tea, and cola drinks.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Adenocard

Along with its needed effects, adenosine (the active ingredient contained in Adenocard) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking adenosine:

Other side effects of Adenocard

Some side effects of adenosine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to adenosine: compounding powder, intravenous solution, sublingual spray.

General adverse events

The most common adverse reactions are flushing, chest discomfort, dyspnea, facial flushing, headache, throat/neck/jaw discomfort, gastrointestinal discomfort, and lightheadedness/dizziness.^[Ref]

Cardiovascular

• Very common (10% or more): Flushing (44%), facial flushing (18%)
• Common (1% to 10%): First degree atrioventricular block, second degree atrioventricular block, hypotension, arrhythmias, ventricular tachycardia
• Uncommon (0.1% to 1%): Bradycardia, sinus tachycardia, palpitations
• Very rare (less than 0.01%): Atrial fibrillation, ventricular fibrillation, Torsade de pointes, severe bradycardia
• Frequency not reported: Myocardial infarction, ventricular arrhythmia, third degree atrioventricular block, sinus exit block, sinus pause, hypertension, skipped beats, atrial extrasystoles, ventricular extrasystoles
• Postmarketing reports: Cardiac arrest/asystole, cardiac failure, tachycardia, prolonged asystole, transient increase in blood pressure^[Ref]

Other

• Very common (10% or more): Chest discomfort (40%)
• Common (1% to 10%): ST segment depression, chest pressure
• Uncommon (0.1% to 1%): Feeling of general discomfort/weakness/pain
• Rare (less than 0.1%): Tinnitus, nipple discomfort
• Frequency not reported: Chest pain, feeling of thoracic constriction/oppression, weakness, T wave changes, ear discomfort, tongue discomfort, heaviness in arms, pressure in groin
• Postmarketing reports: ST segment elevation^[Ref]

Respiratory

• Very common (10% or more): Dyspnea (up to 28%)
• Uncommon (0.1% to 1%): Hyperventilation
• Rare (0.01% to 0.1%): Bronchospasm, nasal congestion
• Very rare (less than 0.01%): Respiratory failure
• Frequency not reported: Cough, throat tightness
• Postmarketing reports: Respiratory arrest/apnea^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 18%), lightheadedness/dizziness (12%)
• Common (1% to 10%): Paresthesia, tingling in arms, numbness, burning sensation
• Uncommon (0.1% to 1%): Metallic taste, head pressure
• Rare (0.01% to 0.1%): Tremor, drowsiness
• Very rare (less than 0.01%): Intracranial hypertension worsening
• Frequency not reported: Scotomas, convulsions
• Postmarketing reports: Cerebrovascular accident, intracranial hemorrhage, seizure, tonic clonic seizures, loss of consciousness/syncope^[Ref]

Musculoskeletal

• Very common (10% or more): Throat/neck/jaw discomfort (15%)
• Common (1% to 10%): Upper extremity discomfort
• Frequency not reported: Back discomfort, lower extremity discomfort, neck and back pain^[Ref]

Gastrointestinal

• Very common (10% or more): Gastrointestinal discomfort (13%)
• Common (1% to 10%): Dry mouth, nausea
• Frequency not reported: Abdominal discomfort
• Postmarketing reports: Vomiting^[Ref]

Psychiatric

• Common (1% to 10%): Nervousness, apprehension
• Frequency not reported: Emotional instability^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Sweating
• Postmarketing reports: Angioedema, urticaria, rash^[Ref]

Ocular

• Uncommon (0.1% to 1%): Blurred vision^[Ref]

Genitourinary

• Rare (less than 0.1%): Urinary urgency
• Frequency not reported: Vaginal pressure^[Ref]

Local

• Very rare (less than 0.01%): Injection site reaction
• Postmarketing reports: Infusion site pain^[Ref]

Hypersensitivity

• Postmarketing reports: Hypersensitivity, anaphylaxis^[Ref]

See also:

Further information

Adenocard side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer