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Acetaminophen / caffeine / phenyltoloxamine Side Effects

Applies to acetaminophen/caffeine/phenyltoloxamine: oral capsule

Cardiovascular

Cardiovascular side effects have included palpitations, hypotension, and cardiac stimulation.[Ref]

Gastrointestinal

Gastrointestinal side effects have included epigastric distress, diarrhea, intestinal cramps, nausea, xerostomia, and dryness of mouth, throat, and nose.[Ref]

Dermatologic

Dermatologic side effects have included urticaria and rash. Acetaminophen has been associated with a risk of rare but potentially fatal serious skin reactions know as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP).[Ref]

Hypersensitivity

Hypersensitivity side effects have included allergic reactions.[Ref]

Hematologic

Hematologic side effects have included thrombocytopenia and agranulocytosis.[Ref]

Musculoskeletal

Musculoskeletal side effects have included muscular weakness.[Ref]

Genitourinary

Genitourinary side effects have included urinary retention.[Ref]

Nervous system

Nervous system side effects have included dizziness, drowsiness, disturbed coordination, inability to concentrate, insomnia, tremors, nervousness, convulsions, irritability, and dependence.[Ref]

Ocular

Ocular side effects have included blurred vision.[Ref]

Renal

Renal side effects have included nephrotoxicity.[Ref]

Metabolic

Metabolic side effects have included hyperglycemia.[Ref]

References

1. "Product Information. Flextra (APAP/caffeine/phenyltoloxamine)." Poly Pharmaceuticals Inc, Quitman, MS.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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