Tri-Norinyl (birth control)
Generic name: ethinyl estradiol and norethindrone (birth control) [ ETH-in-il-ess-tra-DYE-ole-and-nor-ETH-in-drone ]
Brand names: Blisovi 24 FE, Estrostep Fe, Femcon FE, Kaitlib Fe, Lo Loestrin Fe, ... show all 15 brands Loestrin 21 1.5/30, Loestrin 21 1/20, Loestrin Fe 1.5/30, Loestrin Fe 1/20, Microgestin 24 FE, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent
Drug classes: Contraceptives, Sex hormone combinations
The Tri-Norinyl brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Tri-Norinyl?
Tri-Norinyl is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Tri-Norinyl is used as contraception to prevent pregnancy. Tri-Norinyl is also used to treat moderate acne in women who are at least 15 years old and have started having menstrual periods, and who wish to use birth control pills. There are many available brands of ethinyl estradiol and norethindrone. Not all brands are listed on this leaflet.
Tri-Norinyl may also be used for purposes not listed in this medication guide.
Do not use birth control pills if you are pregnant or if you have recently had a baby.
You should not use birth control pills if you have: uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, jaundice caused by pregnancy or birth control pills, or cancer of the breast, uterus/cervix, or vagina.
Smoking, especially if you are older than 35, or taking birth control pills can increase your risk of blood clots, stroke, or heart attack.
Before taking this medicine
Taking birth control pills can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking birth control pills. Your risk is also high when you restart birth control pills after not taking them for 4 weeks or longer.
Smoking can increase your risk of blood clots, stroke, or heart attack caused by birth control pills, especially if you are older than 35.
Do not use if you are pregnant. Stop using Tri-Norinyl and tell your doctor right away if you become pregnant, or if you miss 2 menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking birth control pills.
You should not take birth control pills if you have:
untreated or uncontrolled high blood pressure, or heart disease (chest pain, coronary artery disease, history of heart attack, stroke, or blood clot);
an increased risk of having blood clots due to a heart problem or a hereditary blood disorder;
circulation problems (especially if caused by diabetes);
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;
unusual vaginal bleeding that has not been checked by a doctor;
liver disease or liver cancer;
severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;
a history of jaundice caused by pregnancy or birth control pills;
if you smoke and are over 35 years old; or
if you take any hepatitis C medication containing ombitasvir/paritaprevir/ritonavir with or without dasabuvir.
Tell your doctor if you have ever had:
heart problems, high blood pressure, or if you are prone to having blood clots;
high cholesterol or triglycerides, or if you are overweight;
a seizure or migraine headache;
diabetes, gallbladder disease, underactive thyroid;
liver or kidney disease; or
irregular menstrual cycles, or fibrocystic breast disease, lumps, nodules, or an abnormal mammogram.
Ask a doctor if it is safe to breastfeed while using this medicine.
How should I take birth control pills?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may need to use back-up birth control, such as condoms with spermicide, when you first start using this medication. Follow your doctor's instructions.
Take one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily.
Some birth control packs contain "reminder" pills to keep you on your regular cycle. Your period will usually begin while you are using these reminder pills.
Use a back-up birth control if you are sick with severe vomiting or diarrhea.
You may have breakthrough bleeding. Tell your doctor if it continues or is very heavy.
If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Tri-Norinyl.
While taking birth control pills, you will need to visit your doctor regularly.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Follow the directions on your prescription label and read all medication guides or instruction sheets. Missing a pill increases your risk of becoming pregnant.
If you miss 1 active pill, take 2 pills on the day you remember. Then take 1 pill per day for the rest of the pack.
If you miss 2 active pills in a row in Week 1 or 2, take 2 pills per day for 2 days in a row. Then take 1 pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.
If you miss 2 active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.
If you miss 3 active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.
If you miss 2 or more active pills, you may not have a period during the month. If you miss a period for 2 months in a row, call your doctor because you might be pregnant.
If you miss a reminder pill, throw it away and keep taking 1 reminder pill per day until the pack is empty.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause nausea or vaginal bleeding.
What should I avoid while taking birth control pills?
Do not smoke while taking birth control pills, especially if you are older than 35 years of age.
Birth control pills will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.
Birth control pills side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tri-Norinyl may cause serious side effects. Stop using Tri-Norinyl and call your doctor at once if you have:
signs of a stroke--sudden numbness or weakness, severe headache, slurred speech, problems with vision or balance;
signs of a blood clot in the lung--chest pain, sudden cough or shortness of breath, dizziness, coughing up blood;
signs of a blood clot deep in the body--pain, swelling, or warmth in one leg;
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
liver problems--swelling around your midsection, right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
increased blood pressure--severe headache, blurred vision, pounding in your neck or ears;
depression--mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, new sleep problems, thoughts about hurting yourself;
swelling in your hands, ankles, or feet, or a breast lump; or
a change in the pattern or severity of migraine headaches.
Common side effects of Tri-Norinyl may include:
breast tenderness, or breakthrough bleeding; or
headache, or problems with contact lenses.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect birth control pills?
Tell your doctor about all your other medicines, especially:
anticonvulsants (antiepileptics) such as phenobarbital, phenytoin, and carbamazepine.
This list is not complete. Other drugs may affect Tri-Norinyl, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
More about Tri-Norinyl (ethinyl estradiol / norethindrone)
- Check interactions
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: contraceptives
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