Medically reviewed on July 26, 2017.
What is Timoptic-XE?
Timolol is a beta-blocker that also reduces pressure inside the eye.
Timoptic-XE (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye.
Timoptic-XE may also be used for purposes not listed in this medication guide.
You should not use this medicine if you have asthma or severe COPD, or a serious heart condition (such as "sick sinus syndrome," 2nd or 3rd degree "AV block," severe heart failure, or very slow heartbeats).
Side effects may occur if this medicine is absorbed into your bloodstream. Call your doctor right away if you have: chest pain, trouble breathing, slow heartbeats, muscle weakness, numbness or coldness in your hands or feet, unusual mood or behavior changes, or severe dizziness.
Before taking this medicine
You should not use this medicine if you are allergic to timolol, or if you have:
asthma or severe chronic obstructive pulmonary disease (COPD);
certain serious heart conditions, especially "sick sinus syndrome" or 2nd or 3rd degree "AV block";
severe heart failure; or
slow heartbeats that have caused you to faint.
To make sure Timoptic-XE is safe for you, tell your doctor if you have ever had:
heart disease, a stroke, a blood clot, or circulation problems;
a thyroid disorder;
a muscle disorder such as myasthenia gravis.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Timolol ophthalmic can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Timoptic-XE is not approved for use by anyone younger than 2 years old.
How should I use Timoptic-XE?
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Do not use this medicine while wearing contact lenses. Timoptic-XE may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.
Wash your hands before using the eye drops.
To apply the eye drops:
Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
Wait at least 10 minutes before using any other eye drops your doctor has prescribed.
Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.
Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
It may take a few weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.
If you need surgery, including eye surgery, tell the surgeon ahead of time that you are using Timoptic-XE. You may need to stop using the medicine for a short time.
You should not stop using this medicine suddenly. Follow your doctor's instructions about tapering your dose.
Store at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle tightly closed when not in use. Keep each single-use ampule inside its foil pouch until you are ready to use your dose.
A single-use ampule is for one use only. Throw it away after one use, even if there is still medicine left inside.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include dizziness, headache, slow heartbeats, and trouble breathing.
What should I avoid while using Timoptic-XE?
Timoptic-XE can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.
You may need to use other glaucoma medications in addition to Timoptic-XE. Do not use other eye medications unless your doctor tells you to.
Timoptic-XE side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although the risk of serious side effects is low when timolol is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Call your doctor right away if you have:
wheezing, chest pain, trouble breathing, slow heartbeats;
a light-headed feeling, like you might pass out;
depressed mood, confusion, hallucinations, unusual thoughts or behavior; or
numbness or cold feeling in your hands and feet.
Also call your doctor if you have:
severe stinging or burning after using the eye drops:
eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection); or
blurred vision, tunnel vision, eye pain, or seeing halos around lights.
Common side effects may include:
burning or stinging in your eye;
dry eyes, itching;
feeling like something is in your eye;
red or puffy eyelids; or
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Timoptic-XE?
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with timolol ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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- Drug class: ophthalmic glaucoma agents