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Vyzulta

Generic Name: latanoprostene bunod ophthalmic (la TAN oh PROS teen BUE nod off THAL mik)
Brand Name: Vyzulta

Medically reviewed on December 28, 2017

What is Vyzulta?

Latanoprostene bunod lowers pressure inside the eye by increasing the amount of fluid that drains from the eye.

Vyzulta (for the eyes) is used to treat open-angle glaucoma or other causes of high pressure inside the eye.

Vyzulta may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Vyzulta if you are allergic to it.

To make sure Vyzulta is safe for you, tell your doctor if you have ever had:

  • swelling or an infection in your eye;

  • retinal detachment; or

  • eye surgery or injury affecting the lens of your eye.

Vyzulta may cause a gradual change in the color of your eyes or eyelids and lashes, usually an increase in brown pigment. You may also notice increased growth or thickness of your eyelashes. These changes occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether latanoprostene bunod ophthalmic passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Vyzulta is not approved for use by anyone younger than 16 years old.

How should I use Vyzulta?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

The usual dose of this medicine is 1 drop into the affected eye every evening. Follow your doctor's dosing instructions very carefully.

Do not use this medicine while wearing contact lenses. Vyzulta may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

  • Wait at least 5 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Tell your doctor right away if you have an eye injury or eye infection, or if you plan to have eye surgery.

Store an unopened bottle of the eye drops in a refrigerator. Do not freeze.

After your first use, store the eye drops at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Throw away the medicine after 8 weeks have passed since you first opened the bottle.

What happens if I miss a dose?

Skip the missed dose and take the next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of Vyzulta is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using latanoprostene bunod ophthalmic?

Avoid using too much of Vyzulta, which can actually make it less effective in lowering the pressure inside the eye.

Do not use other eye medications unless your doctor tells you to.

Vyzulta side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using latanoprost and call your doctor at once if you have:

  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);

  • red, swollen, or itchy eyelids;

  • sudden vision changes; or

  • severe pain, burning, stinging, or irritation after using this medicine.

Common side effects may include:

  • puffy eyelids;

  • mild pain or irritation after using the medicine;

  • blurred vision; or

  • feeling like something is in your eye.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Vyzulta?

It is not likely that other drugs you take orally or inject will have an effect on latanoprost used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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