Skip to main content

Tannic-12 S

Generic name: carbetapentane and chlorpheniraminekar-BET-a-PEN-tane-and-KLOR-fen-IR-a-meen ]
Brand names: C-Tanna 12, Tannic-12 S
Drug class: Upper respiratory combinations

Medically reviewed by on Oct 5, 2022. Written by Cerner Multum.

What is Tannic-12 S?

Carbetapentane is a cough suppressant.

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Tannic-12 S is a combination medicine is used to treat cough, sneezing, runny nose, and watery eyes caused by allergies or the common cold.

This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Tannic-12 S may also be used for purposes not listed in this medication guide.


Do not use Tannic-12 S if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Before taking this medicine

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medication if you are allergic to carbetapentane or chlorpheniramine.

To make sure Tannic-12 S is safe for you, tell your doctor if you have:

FDA pregnancy category C. It is not known whether Tannic-12 S will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Carbetapentane and chlorpheniramine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Tannic-12 S?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can affect the results of allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since Tannic-12 S is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Tannic-12 S?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of carbetapentane and chlorpheniramine.

Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine. Antihistamines and cough suppressants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or cough suppressant.

Tannic-12 S side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tannic-12 S may cause serious side effects. Stop using Tannic-12 S and call your doctor at once if you have:

  • fast, pounding, or uneven heartbeat;

  • severe headache, hallucinations, seizure (convulsions);

  • severe dizziness or drowsiness;

  • vision problems;

  • little or no urinating;

  • tremors, severe restlessness; or

  • seizures (convulsions).

Common side effects of Tannic-12 S may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tannic-12 S?

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking Tannic-12 S with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with carbetapentane and chlorpheniramine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

More about Tannic-12 S (carbetapentane / chlorpheniramine)

Patient resources

Other brands

C-Tanna 12

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.