Generic Name: iopamidol (eye oh PAM ih dol)
Brand Name: Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M-200, Isovue-M-300
What is Isovue-250 (iopamidol)?
Iopamidol is in a group of drugs called radiopaque (RAY dee oh payk) contrast agents. Iopamidol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.
Iopamidol is used to help diagnose certain disorders of the heart, brain, blood vessels, and nervous system.
Iopamidol may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Isovue-250 (iopamidol)?
You should not receive iopamidol if you have any type of active infection.
What should I discuss with my health care provider before receiving Isovue-250 (iopamidol)?
Tell your doctor if you have ever had any type of reaction to another contrast agent.
To make sure iopamidol is safe for you, tell your doctor if you have:
liver or kidney disease;
heart disease, including congestive heart failure;
a history of stroke, blood clots, or coronary artery disease;
asthma, hay fever, food allergies;
epilepsy or other seizure disorder;
sickle cell anemia;
an active infection;
pheochromocytoma (tumor of the adrenal gland);
multiple myeloma (bone cancer); or
a thyroid disorder.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether iopamidol passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.
How is Isovue-250 (iopamidol)used?
Iopamidol is injected into a vein or artery through an IV. A healthcare provider will give you this injection.
You may be given medication to prevent certain side effects while you are receiving iopamidol.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when iopamidol is injected.
Drink extra fluids before and after your radiologic test. Iopamidol can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test.
Older adults may need special care to avoid becoming dehydrated. Your kidney function may need to be checked after you have received iopamidol.
Some people receiving iopamidol have had reactions that did not start until 30 to 60 minutes after the medicine was first given. Your caregivers may want to watch you during this period of time after your injection. This is to make sure you do not have any unwanted side effects or delayed reactions.
Iopamidol can interfere with certain medical tests for up to 16 days after you are treated with this medicine. Tell any doctor who treats you that you have recently received iopamidol.
What happens if I miss a dose?
Since iopamidol is used only during your radiologic test, you will not be on a dosing schedule.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving Isovue-250 (iopamidol)?
Do not allow yourself to become dehydrated during the first few days after receiving iopamidol. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor's instructions about the types and amount of fluids you should drink.
Isovue-250 (iopamidol) side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
In rare cases, iopamidol may cause a severe drug reaction that can affect many parts of the body. This type of reaction can start several weeks after you begin using this medicine. Seek medical treatment if you have new or worsening symptoms of fever, facial swelling, a red or blistering skin rash, flu symptoms, swollen glands, feeling weak or tired, severe tingling or numbness, upper stomach pain, loss of appetite, jaundice (yellowing of the skin or eyes), weight loss, pain or burning when you urinate, lower back pain, swelling in your legs or feet, cough, chest pain, or trouble breathing.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
swelling, rapid weight gain, little or no urinating;
wheezing or trouble breathing;
swelling in your neck or throat (enlarged thyroid);
thyroid symptoms--extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain;
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
slow heart rate;
hot flashes, burning sensation;
flushing (warmth, redness, or tingly feeling);
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Isovue-250 (iopamidol)?
Tell your doctor about all your current medicines, especially:
metformin (Glucophage, Glucovance, Actoplus Met, PrandiMet, Avandamet, Kombiglyze, Janumet, Kazano, Invokamet, Jentadueto, Xigduo, Synjardy, Metaglip, and others).
This list is not complete. Other drugs may interact with iopamidol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Isovue-250 (iopamidol)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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- Drug class: non-ionic iodinated contrast media
Related treatment guides
Where can I get more information?
- Your doctor or pharmacist can provide more information about iopamidol.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02.
Date modified: June 01, 2017
Last reviewed: May 09, 2017