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Acoltremon ophthalmic

Generic name: acoltremon ophthalmic
Brand name: Tryptyr
Dosage form: ophthalmic solution (0.003%)
Drug class: Miscellaneous ophthalmic agents

Medically reviewed by Drugs.com on Jul 15, 2025. Written by Cerner Multum.

What is acoltremon ophthalmic?

Acoltremon ophthalmic is used to treat the signs and symptoms of dry eye disease.

Acoltremon ophthalmic may also be used for purposes not listed in this medication guide.

Acoltremon ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Acoltremon ophthalmic may cause serious side effects. Call your doctor at once if you have:

Common side effects of acoltremon ophthalmic may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use acoltremon ophthalmic if you are allergic to it.

Tell your doctor if you are pregnant or breastfeeding.

How should I use acoltremon ophthalmic?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not use while wearing contact lenses. Use the medicine at least 15 minutes before inserting your contact lenses.

Wash your hands before using eye medication.

To apply the eye drops: Pull down your lower eyelid to create a small pocket and squeeze a drop into this pocket. Close your eyes for a few seconds.

It is usually given as 1 drop in each affected eye twice daily. Use immediately after opening the vial.

Wait at least 5 minutes before using any other eye drops.

Do not touch the dropper tip or place it directly on your eye. A contaminated dropper can infect your eye and lead to serious vision problems.

Store acoltremon ophthalmic in the original foil pouch in the refrigerator or at room temperature, in an upright position and tightly closed. If kept at a room temperature, use within 30 days. Do not use after the expiration date.

Throw the medicine away after 7 days of first opening the foil pouch, even if there is still medicine left inside.

Acoltremon ophthalmic dosing information

Usual Adult Dose for Keratoconjunctivitis Sicca:

Instill 1 drop in each eye twice a day (about 12 hours apart)

Use: For the treatment of the signs/symptoms of dry eye disease

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using acoltremon ophthalmic?

Avoid wearing contact lenses while inserting the eye drops. Wait for 15 minutes before putting your lenses in.

What other drugs will affect acoltremon ophthalmic?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

Does Acoltremon ophthalmic interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

More about acoltremon ophthalmic

Patient resources

Other brands

Tryptyr

Professional resources

Other brands

Tryptyr

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.