Clocortolone (Monograph)

Drug class: Corticosteroids
ATC class: D07AB21
VA class: DE200
Chemical name: (6α,11β,16α)-21-(acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS number: 34097-16-0

Medically reviewed by Drugs.com on Jan 20, 2025. Written by ASHP.

Introduction

Clocortolone pivalate is a synthetic fluorinated corticosteroid.

Uses for Clocortolone

Clocortolone pivalate shares the actions of the other topical corticosteroids and is used for the relief of the inflammatory manifestations of corticosteroid-responsive dermatoses.

Clocortolone Dosage and Administration

Topical clocortolone pivalate is applied sparingly in a thin film and rubbed gently into the affected area 1–4 times daily. Occlusive dressings may be used for severe or resistant dermatoses.

Chemistry and Stability

Chemistry

Clocortolone pivalate is a synthetic fluorinated corticosteroid. The drug occurs as a white to yellowish white powder and is sparingly soluble in alcohol.

Stability

Clocortolone pivalate cream should be stored in well-closed containers at 15–30°C; freezing should be avoided.

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

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