What types of hepatitis C (HCV) does Vosevi treat?

Some of the main differences between hepatitis B and C are:

• Hepatitis B virus can be prevented with a vaccine, but not hepatitis C.
• Hepatitis B and C are different viruses, but you can have both hepatitis B and hepatitis C at the same time.
• Over 90% of people infected with hepatitis C who have not received treatment can be cured with 8 to 12 weeks of oral medications, but treatment for hepatitis B, if needed, may be long-term or lifelong.
• There is no cure for hepatitis B, but once you recover from acute hepatitis B, you develop antibodies that protect you from the virus for life.

The newest drugs for the treatment of hepatitis C include Mavyret (glecaprevir and pibrentasvir), Vosevi (sofosbuvir, velpatasvir, and voxilaprevir), and Epclusa (sofosbuvir and velpatasvir). All are FDA-approved for the treatment of chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A), as well as other uses. Continue reading

1. Bailey JR, Barnes E, Cox AL. Approaches, Progress, and Challenges to Hepatitis C Vaccine Development. Gastroenterology. 2019 Jan;156(2):418-430. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340767/
2. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Hepatitis C. March 2020. Available at: https://www.niddk.nih.gov/health-information/liver-disease/viral-hepatitis/hepatitis-c [Accessed August 10, 2021].