What type of drug is Pifeltro (doravirine)?
Pifeltro (doravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used for the treatment of HIV-1 infection.
Non-nucleoside reverse transcriptase inhibitors are antiviral agents that bind non-competitively to HIV-1 reverse transcriptase and prevent viral RNA conversion to DNA. These drugs work by preventing HIV from multiplying in the body. NNRTIs are used in combination with other antiretroviral medicines.
Pifeltro is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg:
- with no prior antiretroviral treatment history, OR
- to replace the current antiretroviral regimen in those who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to doravirine.
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Which medicines should not be taken with Biktarvy?
- Biktarvy is a complete regimen and use with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
- Biktarvy is associated with many drug interactions as it contains three different medicines, increasing your risk for interactions. Have your health care provider check for possible interactions with other prescription medicines, OTCs or herbal you take.
- You should not take Biktarvy with dofetilide (Tikosyn), a drug used for heart rhythm disorders or rifampin (Rifadin), a medicine for tuberculosis (TB). These drugs are contraindicated with the use of Biktarvy.
Who are the actors in the Dovato commercial?
Three real-life patients feature in the Dovato commercial “Detect This” released on May 23, 2022. They are Jovon [surname withheld], Ann Edwards, and Armando [surname withheld]. Continue reading
What if I miss a dose of Biktarvy?
If you miss one dose of Biktarvy (bictegravir, tenofovir, and emtricitabine), take the missed dose as soon as you remember it. If it is almost time for your next dose, just skip the missed dose and take your next dose at the regular time. Try not to miss doses. Taking your medicine as prescribed will help you to keep your HIV under control and help prevent drug resistance. Continue reading
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Drug information
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