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Will I lose weight with Entyvio?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on April 7, 2022.

Official Answer


Weight loss is not reported as a side effect of Entyvio in clinical trials conducted by the drug manufacturer. However, gastrointestinal diseases such as Crohn’s disease or ulcerative colitis can frequently lead to diarrhea, stomach cramps, and a loss of appetite which can result in unintentional weight loss.

Entyvio can also cause liver problems in some people. Liver problems might lead to a loss of appetite, which in turn could lead to weight loss. Tell your doctor right away if you experience any of the following symptoms:

  • tiredness
  • loss of appetite,
  • pain on the right side of your stomach (abdomen)
  • dark urine
  • yellowing of the skin and eyes (jaundice).

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