Skip to main content

How long does azithromycin stay in your system?

Medically reviewed by Drugs.com. Last updated on Aug 19, 2024.

Official Answer by Drugs.com

Azithromycin will be in your system for around 15.5 days, after the last dose.

Azithromycin has an elimination half-life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues.

It takes around 5.5 x elimination half life's for a medicine to be out of your system. Therefore it would take 374 hours about 15.5 days (5.5 x 68 hours) for it to be eliminated from the system. So it'll be in your system for that period of time, after the last dose.

Other factors to consider:

  1. How much and how often you have taken the drug.
  2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
  3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
  4. Body mass – generally the bigger you are the longer a drug will remain in your system.

Read next

What are the best antibiotics for a tooth infection?

There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading

What is the Best Antibiotic for Strep Throat?

Penicillin and amoxicillin are the first-choice antibiotics for strep throat. According to the CDC, Group A Streptococcus (the bacteria that cause Strep throat) has never shown resistance to penicillin, making it the gold standard treatment.

Continue reading

Does azithromycin cure chlamydia: How much / how long?

A single dose of azithromycin 1 gram orally will cure genital chlamydia according to the CDC Guidelines for Sexually Transmitted Diseases but it will take approximately one week to work. You should not have sex during this time, otherwise you may infect your sexual partner with chlamydia. Continue reading

See also:

Related medical questions

Drug information

Related support groups