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Does help ibuprofen reduce fever?

Medically reviewed by Drugs.com. Last updated on April 4, 2025.

Official Answer by Drugs.com

Yes, ibuprofen (Advil, Motrin, generics) does reduce fever. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body.

Ibuprofen can be bought over-the-counter (OTC) without a prescription in the 200 mg strength.

It can be used in adults and children 6 months of age and older. Follow the directions on the OTC Drug Facts Label to determine your dose, or your child's dose, of ibuprofen for fever.

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Naproxen vs ibuprofen: What's the difference?

Ibuprofen is short acting, while naproxen is long acting and more likely to cause an upset stomach. Naproxen also increases the risk of uncontrolled bleeding in people taking blood thinners by 4-fold, and ibuprofen increases the risk 2-fold. Naproxen and ibuprofen are both NSAIDs so they are similar in many ways, but there are important differences. Continue reading

Can you take ibuprofen on an empty stomach?

Despite the common belief that you must take ibuprofen with food, you can safely take low-dose ibuprofen (up to 1200 mg daily in divided doses for 1 to 7 days) on an empty stomach, and this provides faster pain relief than taking ibuprofen with food. Food slows ibuprofen absorption time, although it doesn't affect the total amount absorbed. There is actually no scientific evidence that taking ibuprofen with food prevents stomach irritation. Over-the-counter ibuprofen doses have a low incidence of gastric problems anyway.

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Can you take expired ibuprofen?

Although taking expired ibuprofen is not recommended by the manufacturer, the actual shelf-life is likely to be longer than that indicated by the expiry date, with FDA testing showing many drugs are active for years beyond their expiry date, although specific data on ibuprofen is not available. Within reason, an ibuprofen tablet that is a few months past its expiry date is probably safe to take. Ibuprofen that is years past its expiry date should not be taken. Continue reading

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