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How do you take Nerlynx?

Medically reviewed by Last updated on Sep 20, 2017.

Official Answer


Nerlynx is taken as 6 tablets (for a total of 240 mg) once a day, with food. Treatment is usually continued for one year.

During the first 2 months of treatment, patients should also take a drug called loperamide (Imodium) to manage diarrhea that is a side effect of Nerlynx.

After 2 months, take loperamide as needed. Nerlynx (neratinib), from Puma Biotechnology, Inc., is an oral tyrosine kinase inhibitor therapy used for extended adjuvant treatment (taken after an initial treatment) of early stage HER2-positive breast cancer in women who have been previously treated with the medicine trastuzumab (Herceptin).

Women who took Nerlynx had a longer period of time before their cancer returned, in comparison to women who took placebo.

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