Does Entyvio cause weight gain?
Weight gain was not reported as a side effect of Entyvio in clinical trials conducted by the manufacturer. However, when gastrointestinal diseases such as Crohn’s disease or ulcerative colitis improve, patients who have previously lost weight may gain some back as their healing progresses.
The most common side effects of Entyvio (vedolizumab) include:
- common cold symptoms
- headache
- joint pain
- nausea
- fever
- infections of the nose and throat
- feeling tired
- cough
- bronchitis
- flu symptoms
- back pain
- rash
- itching
- sinus infection
- throat pain
- pain in extremities, such as your arms or legs.
The subcutaneous (injected under the skin) form of Entyvio has also been reported to cause reactions at the injection such as redness, rash, itching, swelling, bruising, and hematoma (a pooling of blood outside of blood vessels.
Related: Does Entyvio cause hair loss?
This is not all the information you need to know about Entyvio (vedolizumab) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
References
- Takeda Pharmaceuticals, Inc. Entyvio (vedolizumab) prescribing information. Deerfield, IL; 4/2024. Accessed July 19, 2025 at https://content.takeda.com/?contenttype=PI&product=ENTY&language=ENG&country=USA&documentnumber=1
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How much does Entyvio cost per month?
The cash price for Entyvio is $9,135 for a 300 mg powder for intravenous (IV) injection, using an online coupon, but most people do not pay this amount. After your initial 2 injections in the first month, IV Enytvio is normally given every 8 weeks starting at week 6. It also comes as a subcutaneous (under the skin) injection that is given every 2 weeks. Continue reading
Is Entyvio an immunosuppressant or a biologic?
Entyvio (generic name: vedolizumab) is a biologic therapy approved for the treatment of ulcerative colitis and Crohn’s disease. Entyvio has no known systemic (whole body) immunosuppressive effects, but still has a risk of infections, some that might be serious.
Continue reading
How long does it take Entyvio to start working?
Entyvio may reduce your gut inflammation in about 6 weeks. Over time, Entyvio can help you to have fewer symptoms, go into remission, and reduce or stop the use of corticosteroids. In remission, your symptoms such as stomach pain and cramping, diarrhea and fatigue will go away. Continue reading
See also:
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- Does Entyvio cause joint pain?
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- Does Medicaid cover Entyvio?
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- How is Entyvio administered?
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- How does Entyvio copay assistance work?
Drug information
- Entyvio Information for Consumers
- Entyvio prescribing info & package insert (for Health Professionals)
- Side Effects of Entyvio (detailed)
- Entyvio user reviews (167)
Related support groups
- Entyvio (24 questions, 34 members)
- Ulcerative Colitis (75 questions, 188 members)
- Crohn's Disease (62 questions, 286 members)