How do you calculate the dosage for Carnexiv?
In the U.S., Carnexiv has been discontinued by the manufacturer.
The total daily dosage of Carnexiv should be 70% of the total daily dose of oral carbamazepine, divided into 4 equal doses and given every 6 hours.
- For example, for a patient taking a total daily oral carbamazepine dose of 400 mg/day, the corresponding total daily dose of Carnexiv would be 280 mg/day. This translates into 70 mg of Carnexiv to be given intravenously every 6 hours.
- Patients should be switched back to their previous oral carbamazepine regimen as soon as clinically appropriate.
- Use of Carnexiv is not recommended for periods longer than 7 days.
Health Care providers can also determine dose by reviewing the table in the manufacturer's package labeling.
Carnexiv (carbamazepine) is the first intravenous (IV) injection formulation for the antiseizure drug carbamazepine. Carnexiv is used as short-term replacement therapy for oral carbamazepine when taking carbamazepine by mouth is temporarily not feasible. It is used in adults with the following seizure types:
- Partial seizures with complex symptomatology
- Generalized tonic-clonic seizures
- Mixed seizure patterns which include the above, or other partial or generalized seizures
This is not all the information you need to know about Carnexiv (carbamazepine) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full product information here, and discuss this information and any questions you have with your doctor or other health care provider.
References
- Carnexiv (carbamazepine) [product information]. Lundbeck, Deerfield, Ill. Revised 10/2016. Accessed March 16, 2021 at https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/206030s000lbl.pdf
- Drugs@FDA. Carnexiv. AccessedMarch 16, 2021 at https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm
Read next
What type of epilepsy is Diacomit used to treat?
Diacomit (stiripentol) is an oral anticonvulsant used with clobazam (Onfi) for seizures associated with Dravet syndrome in patients 6 months of age and older, weighing at least 7 kg (15.4 lbs), and taking the benzodiazepine clobazam (Onfi). Diacomit is not used alone to treat Dravet Syndrome, a rare, genetic form of epilepsy. It usually begins in infancy, often during a fever due to illness or vaccination. Continue reading
How long does it take for Lyrica (pregabalin) to work?
In clinical studies with Lyrica, some patients experienced a decrease in pain as early as the first week, which persisted during the entire study period of 5 to 13 weeks. Continue reading
How long does Lyrica (pregabalin) stay in your system?
Lyrica (pregabalin) will stay in your blood (plasma) for about 35 hours, but its clinical effect may wear off before this time. Studies have shown pregabalin to be detectable in urine for up to 5 to 6 days. Continue reading
See also:
Related medical questions
- Lyrica vs Gabapentin: What's the difference?
- Can you stop Lyrica (pregabalin) cold turkey?
- How effective is Topamax (topiramate) for weight loss?
- CBD Oil: What are 9 Proven or Possible Health Benefits?
- Does Lyrica (pregabalin) make you sleepy?
- Is gabapentin addictive?
- Should gabapentin be taken with food?
- What not to take with topiramate?
- Can you stop taking Topamax suddenly?
- Does Topamax (topiramate) cause hair loss?
- Can you drink alcohol while taking Topamax (topiramate)?
- How long does it take for Topamax to start working?
- How long does Topamax stay in your system?
- How long does Trileptal withdrawal last?
- How long does it take for Trileptal to work?
- Does Trileptal cause weight gain?
- What is the difference between Briviact and Keppra?
- Is Topamax (topiramate) a controlled substance?
- CBD vs THC vs Cannabis: What's the difference between them?
- How does Trokendi XR help with weight loss?
- Are Topamax and Trokendi XR the same thing?
- Aptiom vs Keppra, what is the difference?
- Can Briviact be cut in half or crushed?
- Is Oxtellar XR the same as Trileptal?
- When is the best time of day to take Trokendi XR?
- What is Onfi used to treat?
- How long does it take for Oxtellar XR to work?
Drug information
- Carnexiv Information for Consumers
- Carnexiv prescribing info & package insert (for Health Professionals)
- Side Effects of Carnexiv (detailed)