Skip to main content

How do you calculate the dosage for Carnexiv?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on March 6, 2025.

Official answer

by Drugs.com

In the U.S., Carnexiv has been discontinued by the manufacturer.

The total daily dosage of Carnexiv should be 70% of the total daily dose of oral carbamazepine, divided into 4 equal doses and given every 6 hours.

  • For example, for a patient taking a total daily oral carbamazepine dose of 400 mg/day, the corresponding total daily dose of Carnexiv would be 280 mg/day. This translates into 70 mg of Carnexiv to be given intravenously every 6 hours.
  • Patients should be switched back to their previous oral carbamazepine regimen as soon as clinically appropriate.
  • Use of Carnexiv is not recommended for periods longer than 7 days.

Health Care providers can also determine dose by reviewing the table in the manufacturer's package labeling.

Carnexiv (carbamazepine) is the first intravenous (IV) injection formulation for the antiseizure drug carbamazepine. Carnexiv is used as short-term replacement therapy for oral carbamazepine when taking carbamazepine by mouth is temporarily not feasible. It is used in adults with the following seizure types:

  • Partial seizures with complex symptomatology
  • Generalized tonic-clonic seizures
  • Mixed seizure patterns which include the above, or other partial or generalized seizures

This is not all the information you need to know about Carnexiv (carbamazepine) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full product information here, and discuss this information and any questions you have with your doctor or other health care provider.

References

Read next

What type of epilepsy is Diacomit used to treat?

Diacomit (stiripentol) is an oral anticonvulsant used with clobazam (Onfi) for seizures associated with Dravet syndrome in patients 6 months of age and older, weighing at least 7 kg (15.4 lbs), and taking the benzodiazepine clobazam (Onfi). Diacomit is not used alone to treat Dravet Syndrome, a rare, genetic form of epilepsy. It usually begins in infancy, often during a fever due to illness or vaccination. Continue reading

How long does Lyrica stay in your system?

Lyrica (pregabalin) will stay in your blood (plasma) for about 35 hours, but its clinical effect may wear off before this time. Studies have shown pregabalin to be detectable in urine for up to 5 to 6 days. Continue reading

Does topiramate cause weight loss?

Yes, topiramate (Topamax) has been shown to cause weight loss when used for both seizure control and migraine prevention. Topiramate by itself is not specifically approved by the FDA for weight loss, but is used in an "off-label" fashion for this condition. Qsymia, an extended-release medicine that contains phentermine and topiramate, is FDA approved for weight loss, along with diet and exercise. Continue reading

Related medical questions

Drug information

Related support groups