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Imatinib

In the US, Imatinib (imatinib systemic) is a member of the drug class BCR-ABL tyrosine kinase inhibitors and is used to treat Acute Lymphoblastic Leukemia, Chronic Eosinophilic Leukemia, Chronic Myelogenous Leukemia, Dermatofibrosarcoma Protuberans, Gastrointestinal Stromal Tumor, Hypereosinophilic Syndrome, Myelodysplastic Diseases, Myeloproliferative Disorders and Systemic Mastocytosis.

US matches:

UK matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XE01

CAS registry number (Chemical Abstracts Service)

0152459-95-5

Chemical Formula

C29-H31-N7-O

Molecular Weight

493

Therapeutic Category

Antineoplastic agent: Tyrosine kinase inhibitor

Chemical Names

alpha-(4-metyl-1-piperazinyl)-3'-[[4-(3-pyridyl)-2-pyrimidinyl]amino]-p-tolu-p-toluidide- (WHO)

Benzamide, 4-((4-metyl)-1-piperazinyl)metyl)-N-(4-metyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)-

Foreign Names

  • Imatinibum (Latin)
  • Imatinib (German)
  • Imatinib (French)
  • Imatinib (Spanish)

Generic Names

  • Imatinib (OS: BAN)
  • CGP 57148 (IS)
  • Imatinib Mesilate (OS: BAN, JAN)
  • Imatinib Mesylate (OS: USAN)
  • CGP 57148B (IS: Novartis)
  • chronic myeloid leukemia (IS: CML)
  • CML (IS)
  • Imatinib Mesylate (IS)
  • STI 571 (IS: Novartis)
  • Imatinib mesilate (PH: Ph. Eur. 8)
  • Imatinibi mesilas (PH: Ph. Eur. 8)
  • Imatinibmesilat (PH: Ph. Eur. 8)

Brand Names

International Drug Name Search

Glossary

TermDefinition
BANBritish Approved Name
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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