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Ibrutinib

In the US, Ibrutinib (ibrutinib systemic) is a member of the drug class multikinase inhibitors and is used to treat Chronic Lymphocytic Leukemia, Lymphoma, Mantle Cell Lymphoma, Non-Hodgkin's Lymphoma and Waldenström Macroglobulinemia.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XE27

CAS registry number (Chemical Abstracts Service)

0936563-96-1

Chemical Formula

C25-H24-N6-O2

Molecular Weight

440

Therapeutic Category

Antineoplastic agent: Tyrosine kinase inhibitor

Chemical Name

1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one (WHO)

Foreign Names

  • Ibrutinibum (Latin)
  • Ibrutinib (German)
  • Ibrutinib (French)
  • Ibrutinib (Spanish)

Generic Names

  • Ibrutinib (OS: USAN, JAN)
  • UNII-1X70OSD4VX (IS)
  • Ibrutinib (PH: JP XVI)

Brand Names

  • Imbruvica
    Catalent CTS, Israel; Janssen, Ireland; Janssen, Slovenia; Janssen, Slovakia; Janssen-Cilag, Switzerland; Janssen-Cilag, Germany; Janssen-Cilag, United Kingdom; Janssen-Cilag, Poland; Johnson & Johnson, Croatia (Hrvatska); Pharmacyclics, United States
  • IMBRUVICA
    Janssen-Cilag, France

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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