Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Cardoxin (digoxin)
- landiolol
Interactions between your drugs
digoxin landiolol
Applies to: Cardoxin (digoxin), landiolol
Consumer information for this interaction is not currently available.
MONITOR CLOSELY: Coadministration of landiolol with positive inotropes, vasoconstrictors, or sympathomimetic agents may decrease the therapeutic effects of landiolol. According to the package labeling, concomitant use reduced landiolol's heart rate and blood pressure lowering effects. In addition, concomitant dobutamine also reduced landiolol's effect on PR-interval prolongation.
MANAGEMENT: If coadministration is clinically necessary, careful titration of the landiolol infusion and close hemodynamic monitoring is advised. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.
Drug and food interactions
digoxin food
Applies to: Cardoxin (digoxin)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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