Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- solriamfetol
- Urolene Blue (methylene blue)
Interactions between your drugs
methylene blue solriamfetol
Applies to: Urolene Blue (methylene blue), solriamfetol
CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine.
MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol.
References (1)
- (2019) "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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